Introduction: Glioblastoma multiform is the most common malignant brain tumor, with an invasive nature. Despite the development of conventional therapies such as surgery, radiotherapy and chemotherapy, because of high recurrence rates, the prognosis remains very poor. Over the last decade, nanotechnology has represented an innovative method as nanoparticle-based drug delivery ...

Magnetic-mediated hyperthermia (MMH) is a promising local thermotherapy approach for cancer treatment. The present study investigated the feasibility and effectiveness of MMH in esophageal cancer using a rabbit tumor model. The therapeutic effect of two hyperthermia approaches, magnetic stent hyperthermia (MSH), in which heat is induced by the clinical stent that is placed inside the esophagus,...

The hydrodynamics of magnetic fluids, often termed ferrofluids, has been an active area of research since the mid 1960s. However, it is only in the past twenty years that these fluids have begun to be used in magnetic resonance imaging (MRI) where they have found application as contrast agents, improving the contrast to noise ratio of the received MR intensity. The major goal of this work was t...

Abstract Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are more and used in biomedical applications such as therapy (treatment for certain cancers, hyperthermia), diagnostic (contrast agent Magnetic Resonance Imaging) or both. For these applications, SPIONs must be stable an aqueous solution, monodisperse, with a narrow size distribution without aggregation. To obtain nanoparticles, micro...

Hyperthermia treatment, generated by magnetic nanoparticles (MNPs) is promising since it is tumour-focused, minimally invasive and uniform. The most unique feature of magnetic nanoparticles is its reaction and modulation by a magnetic force basically responsible for enabling its potential as heating mediators for cancer therapy. In magnetic nanoparticle hyperthermia, a tumour is preferentially ...

This work reports important advances in the study of magnetic nanoparticles (MNPs) related to their application in different research fields such as magnetic hyperthermia. Nanotherapy based on targeted nanoparticles could become an attractive alternative to conventional oncologic treatments as it allows a local heating in tumoral surroundings without damage to healthy tissue. RGD-peptide-conjug...

In this study, magnetic iron oxide nanoparticle induced hyperthermia is applied for treatment of head and neck cancer using a mouse xenograft model of human head and neck cancer (Tu212 cell line). A hyperthermia system for heating iron oxide nanoparticles was developed by using alternating magnetic fields. Both theoretical simulation and experimental studies were performed to verify the thermot...

We show how tumour heating in magnetic hyperthermia can become more homogeneous through exploitation of magnetisation dynamics interacting particles.

BACKGROUND The effects of inductive hyperthermia on lung cancer have yet to be fully investigated. Magnetic nanoparticles used in inductive hyperthermia are made-to-order and expensive. This study was performed to investigate the use of ferucarbotran in inductive hyperthermia and to clarify whether inductive hyperthermia using ferucarbotran promotes antitumor effects in vivo using a lung cancer...