Title:Chlorophytum borivilianum (Safed Musli) root extract prevents impairment in characteristics and elevation of oxidative stress in sperm of streptozotocin-induced adult male diabetic Wistar rats

Evaluation of hypoglycemic activity of inflorescence of Borassus flabellifer extract in male wistar rats has been investigated. Antidiabetic potentials were studies by the orally administration of plant extract at the doses of 150, 300 and 600 mg/kg in streptozocin-induced diabetic male wistar rats. Treatment of streptozocin-induced diabetic male wistar rats with the extracts caused a signifi...

background : the rapid  development of  the mining and industry activities increased and many toxic metals  in the environment of the earth's crust has been dissipated  and t  has taken  risks to human exposure, inhalation. today evidence of many  diseases associated with environmental  factors  harmful to repellent bio systems is increasing gradually , the majority of these factors  were man-m...

abstract objective: the previous studies indicated that the tlrs especially toll-like receptor 4) tlr4 (are involved in the process of diabetes. the aim of the present research was to investigate the time course expression pattern of tlr4-a main component of innate immune system- in mrna levels in the heart tissue of diabetic male wistar rats. materials and methods: in this research, adult wist...

This investigation was designed to determine the effects of administration of honey on sperm parameters and fertility potential in adult male Wistar rats. A total of forty five rats (thirty males and fifteen females) weighing between 225±5g were used for the study. The male rats were divided into 3 groups i.e., 2 experimental and 1 control groups of ten rats each, (n=10). The 15 female rats wer...

[Purpose] This study investigated the effect of aging on muscle regeneration in rats. [Participants and Methods] Male Wistar rats were divided into 3 groups 10-week-old, 24-week-old, 95-week-old animals. We administered a cardiotoxin to soleus create skeletal injury model, physiological analysis histological was performed at 1, 2, 4, 7, 14, 28 days after administration. [Results] The cross-sect...

We have investigated if EWH could counteract or prevent cardiovascular damage induced by high level of Cd exposure in rats. Male Wistar rats were treated for 14 days with: (A) Untreated - intraperitoneal (i.p.) injections distilled water and tap gavage; (B) ? 1 mg/kg bw/day CdCl2 (C) – mg/kg/day (D) CdEWH both treatments. prevented the increase on systolic blood pressure, vascular dysfunction, ...

Leaky endothelial junctions occurring during cell turnover have been postulated to be a major pathway for enhanced lipoprotein transport across the vascular endothelial layer, which leads to the development of atherosclerosis. Because hypertension has been well documented as one of the major risk factors for atherosclerosis, we explored the possibility that hypertension accelerates atherogenesi...

The present work investigated repeated dose and reproductive toxicity of Calebin A in Wistar rats. A study for assessing the mutagenic potential of Calebin A through an AMES test is also described. Calebin A was orally administered to groups of 10 male and/or 10 female Wistar rats each, assigned to three dose levels (20, 50 and 100 mg/kg/body weight) once daily for 90 consecutive days. None of ...

Cancer is a leading cause of death worldwide and its development is frequently associated with oxidative stress-induced by carcinogens such as arsenicals. Most foods are basically health-promoting or disease-preventing and a typical example of such type is honey. This study was undertaken to investigate the ameliorative effects of Acacia honey on sodium arsenite-induced oxidative stress in the ...