Congenital melanocytic nevi are commonly encountered in clinical practice. Although the development of malignant melanoma arising in small and intermediate congenital melanocytic nevi is rare, there is a significant risk of malignant degeneration associated with large congenital melanocytic nevi, in particular those that arise on the torso in the so-called "bathing trunk" distribution, where th...

introduction wilson’s disease is an autosomal recessive disorder, characterized by a disturbance in copper metabolism that leads to copper overload in different tissues of the body. because of various manifestations of wilson’s disease, physicians should have high index suspicion when patients manifest any type of liver disease, neurologic and psychiatric signs and symptoms. discussion wilson’s...

conclusions significant improvement was noted at womac scale (pain level; 5 points, stiffness level; 2 points, physical function loss; 15 points, and total womac 22 points). osteoarthritis level of the patient was improved to grade i at radiological evaluation after a year. our case is the report that presents radiological evidence in addition to clinical findings of improvement of osteoarthrit...

Cells from normal rat brain tissue did not survive and few cells could be found 1 d after grafting. In contrast, cells from a glioma and a carcinogen-treated rat brain survived well and many mitoses were observed. These malignant cells also invaded the limb. The behaviour of normal and malignant cells was followed at shorter times after grafting and some invasion by the normal cells was detecte...

Ciliated hepatic foregut cysts (CHFC) are rare, typically benign, lesions whose incidence has been increasing recently. Despite this increase in incidence, they remain rare and several key characteristics remain poorly understood, including the range of presentation and the risk of malignant conversion. To better understand CHFC, an extensive review of the international literature was performed...

Sir, Follicular mucinosis (FM) is a non-speci¢c histological reaction pattern characterized by mucinous degeneration of the outer sheath of follicles and sebaceous glands, accompanied by a variable in£ammatory cell in¢ltrate (1). The clinical expression is extremely variable. It may occur as a primary disorder or associated with benign or malignant diseases (2 ^ 4). We describe a patient who de...

BACKGROUND Brunner's hamartoma is a quite rare neoformation whose origin is not completely clear. METHODS A case of a 69-year-old man with recurrent epigastric pain and an endoscopic finding of a duodenal mass is reported. RESULTS The complete removal of hamartoma can give a complete remission of symptoms. CONCLUSIONS Hamartoma can be only diagnosed by endoscopy and histological exam; its...

Proliferating trichilemmal cysts, also known as pilar tumors, are slow-growing lobulated masses most commonly found on the scalp of elderly women. We present the case of a 69-year-old woman with a 25-year history of multiple enlarging scalp masses. The patient was evaluated for surgical consultation after the dominant mass presented with malignant degeneration. A CT of the head revealed multipl...

Multiple hereditary exostoses is an autosomal dominant condition characterized by numerous benign osteochondromas. Complications are rare and can include deformity, growth abnormality, fracture, adventitial bursa formation, local mass effect on a nerve, malignant degeneration, and vascular complications including stenosis, occlusion, arteriovenous fistula, and pseudoaneurysm. We present a case ...

Solitary osteochondromas are common benign long bone tumors originating from cartilage. They may produce a wide variety of symptoms and complications depending on their spinal location. These may include compressive myelopathy, nerve root compression, pathologic fracture and malignant degeneration, or in some cases only pain. Solitary cervical spine osteochondromas have been reported mostly in ...