BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is caused by multiple factors including hepatic oxidative stress, lipotoxicity, and mitochondrial dysfunction. Obesity is among the risk factors for NAFLD alongside type 2 diabetes mellitus and hyperlipidemia. α- mangostin (α-MG) extracts from the pericarps of mangosteen (Garcinia mangostana Linn.) may regulate high fat diet-induced hepatic s...

Dental caries occurs due to the demineralization of tooth structure caused by microorganisms in colonies called biofilms. One involved dental is Streptococcus mutans. Oral mouthwash, addition mechanical cleaning, known prevent growth oral microorganisms. Mangosteen as an anti-cancer ingredient with high anti-bacterial properties. This study aims identify effectiveness mangosteen skin extract (G...

Soursop fruit has been used in folklore for the management of type-2 diabetes and hypertension with limited information on the scientific backing. This study investigated the effects of aqueous extracts (1 : 100 w/v) of Soursop fruit part (pericarp, pulp, and seed) on key enzymes linked to type-2 diabetes (α-amylase and α-glucosidase) and hypertension [angiotensin-I converting enzyme (ACE)]. Ra...

The antinociceptive effect of Elaeagnus angustifolia fruits was studied in mice. The antinociceptive effect of ethanolic and boiling water extracts was studied using two thermal stimuli, the hot-plate and tail-flick tests. The intraperitoneal and oral administration of the ethanolic extract of seed 0.75-7.00 g/kg), but not pericarp and medulla had significant antinociceptive activity in the...

BACKGROUND Leptospirosis, one of the most widespread zoonotic infectious diseases worldwide, is caused by spirochetes bacteria of the genus Leptospira. The present study examined inhibitory activity of purified xanthones and crude extracts from Garcinia mangostana against both non-pathogenic and pathogenic leptospira. Synergy between γ-mangostin and penicillin G against leptospires was also det...

Objective: To investigate In vitro anticancer activity of ethanolic extract pericarp and seed parts Momordica charantia on colon cancer cell line.Materials Methods: was carried out by 3 (4,5 dimethylthiazol 2 yl) 2,5 diphenyltetrazolium bromide assay. Different concentrations the extracts were tested lines HT29.Results Discussion: IC 50 value determined measuring absorbance at 570nm. The IC50 P...

Disinfectant is one of the materials that can be used to inactivate pathogenic microorganisms, but most disinfectants in community are made from synthetic chemicals harmful environment. The purpose this study was synthesize and evaluate antimicrobial activity silver (Ag) nanoparticles-mangosteen rind extract as an active ingredient environmentally friendly disinfectant formula. synthesis proces...