IM A G E : LA G U N A D E S IG N /G E TT Y IM A G E S The United States Pharmacopeial Convention (USP) Therapeutic Peptides Expert Panel was formed in 2013 to evaluate quality attributes for synthetic peptides based on currently available regulatory guidance and expectations. Public quality standards for drug products and drug substances are developed by USP and enforceable by FDA. This series ...

The advent of flat-panel displays has opened the era of macroelectronics. Enthusiasm is gathering to develop macroelectronics as a platform for many technologies, ranging from paper-like displays to thin-film solar cells, technologies that aim to address the essential societal needs for easily accessible information, renewable energy, and sustainable environment. The widespread use of these lar...

Previous studies have proved that partial information transmission can be found between intensity and pitch. In our last study, it was demonstrated that the timbre attribute can be transmitted as partial information between timbre and intensity. We manipulated the two attributes of stimulus, namely, timbre (piano vs. violin) and pitch (high vs. low), to find out whether they also have partial i...

Globalization of business and the competitiveness of manufacturing have motivated companies to improve the facilities to respond to the market requirements. Machine tool selection plays a major role in the improvement of productivity, flexibility in uncertain manufacturing. The objective of this study is to present the simple approach for machine tool selection based on the integration of consi...

Competitive environments are driving manufacturing organisations to react quickly to unpredictable changes and customer opportunities. To face these new challenges, manufacturing organisations require the support of information technology/systems in their operations. An information technology/systems infrastructure capable of coping with these changes is in part responsible for determining the ...

This paper presents a fuzzy CBR (case-based reasoning) technique for generating new product ideas from a product database for enhancing the functions of a given product (called the baseline product). In the database, a product is modeled by a 100-attribute vector, 87 of which are used to model the use-scenario and 13 are used to describe the manufacturing/recycling features. Based on the usesce...

A parametric voxel-based jewelry modeler is developed for designing carved bangles of sophisticated craftsmanship. Carved jewelry is the form of jewelry having small internal repeated cavities as engraved with a thin sharp tool on the surface of sheet metal. The parameters’ values are defined by the user and modeling of the jewelry design is carried out by the modeler based on the specified val...

The paper presents a dropwise additive manufacturing process for pharmaceutical products (DAMPP) as an alternative to conventional methods. This mini manufacturing process for the production of personalized pharmaceutical products utilizes drop-on-demand (DoD) printing technology for the deposition of active pharmaceutical ingredient (API) onto edible substrates. Here we present a process contr...

Dispatching rules are usually applied to schedule jobs in Flexible Manufacturing Systems (FMSs) dynamically. Despite their frequent use, one of the drawbacks that they display is that the state the manufacturing system is in dictates the level of performance of the rule. As no rule is better than all the other rules for all system states, it would highly desirable to know which rule is the most...

Dispatching rules are usually applied to schedule jobs in Flexible Manufacturing Systems (FMSs) dynamically. Despite their frequent use, one of the drawbacks that they display is that the state the manufacturing system is in dictates the level of performance of the rule. As no rule is better than all the other rules for all system states, it would highly desirable to know which rule is the most...