Prognostic or therapeutic classification of diseases is often based on clinical genetic characteristics at diagnosis response landmarks determined a certain time point treatment. On the other hand, there are more and means, such as molecular markers sensor data, that allow for quantification disease parameters over time. Although general value time-resolved monitoring widely accepted, full pote...

Key-words Name of the disease/Included diseases Definition Differential diagnosis Aetiology/pathophysiology Clinical description Diagnostic methods Epidemiology Genetic counselling Antenatal diagnosis Management including treatment Unresolved questions References Abstract Classical dyskeratosis congenita (DC) is a rare multisystem disorder with a prevalence estimated to 1 in 1,000,000. DC is ch...

s David Alonso-Gutiérrez On a different proof of Junge’s estimate for the isotropy constant of polytopes Tuesday 4:30–4:55 p.m. Abstract: It was proved by M. Junge that the isotropy constant of any symmetric polytope with 2N vertices is bounded by C logN . We give a different proof of this result, which shows that the same estimate is true when the polytope is nonsymmetric with N vertices. It w...