Under a complex technical condition, similar to such used in extreme value theory, we find the rate q(ε) at which a stochastic process with stationary increments ξ should be sampled, for the sampled process ξ(⌊·/q(ε)⌋q(ε)) to deviate from ξ by at most ε, with a given probability, asymptotically as ε ↓ 0. The canonical application is to discretization errors in computer simulation of stochastic ...

We use psychophysical techniques to investigate the neural mechanisms subserving suprathreshold chromatic discrimination in human vision. We address two questions: (1) How are the postreceptoral detection mechanism responses combined to form suprathreshold chromatic discriminators? and (2) How do these discriminators contribute to color perception? We use a pedestal paradigm in which the subjec...

Using implanted archival tags, we examined the effects of meal caloric value, food type (sardine or squid) and ambient temperature on the magnitude and duration of the heat increment of feeding in three captive juvenile Pacific bluefin tuna. The objective of our study was to develop a model that can be used to estimate energy intake in wild fish of similar body mass. Both the magnitude and dura...

Purpose. The aim of this study was to directly compare the efficacy and the safety of the two agents for postmenopausal women. Methods/Principal Findings. Electronic databases were searched for relevant articles that met our predefined inclusion criteria. Seven randomized controlled trials (RCTs) involving 4054 women were identified and included. Although Aln was more effective than Rlx in incr...

OBJECTIVE Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis. APPROACH AND RESULTS We evaluated cross-sectional and longitudinal associations of 25-OHD and PTH with carotid intima-media thickness (IMT) and car...

Dysregulation of the WNT/β-catenin (CTNNB1) signaling pathway is implicated in colorectal carcinoma and metabolic diseases. Considering these roles and cancer prevention, we hypothesized that tumor CTNNB1 status might influence cellular sensitivity to obesity and physical activity. In clinical follow-up of 109,046 women in the Nurses' Health Study and 47,684 men in the Health Professionals Foll...

The use of object-oriented frameworks is one way to increase productivity by reusing both design and code. In this paper, a framework-based application is viewed as composed by a framework part and an increment. It is difficult to relate the intended behaviour of the final application to specific increment requirements, it is therefore difficult to test the increment using traditional testing m...

In top–bottom seesaw and topflavor model, there may exist extra Higgs bosons vector-like fermions, we have examined the W-mass anomaly reported by CDF II in these frames. We found that W-boson mass data constrains parameter [Formula: see text] strictly two models, respectively, while constraints on other parameters such as text], are quite weak. Therefore, conclude increment is sensitive to but...