background: preeclampsia is a disorder unique to pregnancy and has long been recognized as an important contributor of maternal and fetal morbidity and mortality. it is suggested that cytokines such as tumor necrosis factor-alpha (tnf-α) have an important role in the pathogenesis of preeclampsia and may cause generalized endothelial dysfunction. objective: the aim of this study was comparison o...

Background. In 2021, stunting in Indonesia remains high at 24.4%. Indonesian government has a target to decrease prevalence become 14% 2024. Jember is one of district East Java with 23,4%. First thousand days life influenced stunting, and maternal risk factor determinants stunting. was known as 4T, which Too young, old, closed much. Objectives. To analyze Maternal Risk Factor (4T) families dist...

Postnatal maternal separation increases hypothalamic corticotropin-releasing factor (CRF) gene expression and hypothalamic-pituitary-adrenal (HPA) and behavioral responses to stress. We report here that environmental enrichment during the peripubertal period completely reverses the effects of maternal separation on both HPA and behavioral responses to stress, with no effect on CRF mRNA expressi...

objective(s):we investigated the influence of genetic variation of the transforming growth-factor alpha (tgfa) locus on the relationship between smoking and oral clefts. materials and methods:in this study 105 iranian infants with non-syndromic cleft lip/palate and 218 controls with non-cleft birth defects were examined to test for associations among maternal exposures, genetic markers, and ora...

Title of Dissertation: DOMESTIC VIOLENCE EXPOSURE, MATERNAL EDUCATION, AND MATERNAL AUTONOMY AS PREDICTORS OF INDIAN WOMEN’S USE OF MATERNAL HEALTH SERVICES AND INFANT LOW BIRTH WEIGHT Mili Duggal, Doctor of Philosophy, 2015 Dissertation directed by: Professor Sally A. Koblinsky Department of Family Science India contributes disproportionately to the world’s maternal mortality ratio and rate of...

INTRODUCTION Preeclampsia is associated with increased levels of the circulating anti-angiogenic factor sFlt-1 as well as with an excessive shedding of placenta-derived multinucleated syncytial aggregates into the maternal circulation. However, it remains unclear whether these aggregates are transcriptionally active in the maternal organs and can therefore contribute to the systemic manifestati...