A Chinese family with hemoglobin H in the propositus has been reinvestigated. Although the original propositus is now deceased, a sister has the same hematological manifestations. Her hemoglobin, like that of the deceased sister, contains hemoglobins A, H, and Bart's. In addition, however, two minor components have been detected. These minor components appear to have abnormal alpha-chains and a...

Hematological parameters, serum cobalamin and folate levels, and the concentrations of the functional markers plasma methylmalonic acid and total homocysteine were determined in 173 newborns and 46 infants at 6 weeks to see whether maternal smoking influences the hematological parameters and the vitamin status of the newborn. At birth, there was a strong inverse correlation between the number o...

OBJECTIVE We sought to determine whether the timing of balloon tamponade (BT) and uterine artery embolization is associated with morbidity among women with postpartum hemorrhage (PPH). STUDY DESIGN This is a cohort study of women with PPH at a single tertiary academic institution. Patient demographics, delivery outcomes (eg, labor augmentation, route of delivery), and PPH-specific data (eg, e...

BACKGROUND The most appropriate dose of iron to prevent maternal anemia is still unclear. OBJECTIVE We assessed the dose-response relation between maternal hemoglobin and 2 prenatal iron supplements. DESIGN An intention-to-treat, double-blind, randomized controlled trial compared 30 mg Fe + folic acid and 13 other micronutrients (UNIMMAP; UNICEF/WHO/UNU multiple micronutrient supplement for...

Anemia is highly prevalent globally, estimated at 40-50% in women of reproductive age. Prior studies have produced inconclusive evidence as to the association between maternal anemia and intrauterine growth restriction (IUGR). We conducted a systematic review of the literature containing associations between maternal anemia and small for gestational age (SGA) outcomes (as a proxy for IUGR). A m...

OBJECTIVE To evaluate the safety of cesarean myomectomy in large myomas sized >5 cm. METHODS One hundred sixty-five pregnant women with myomas who delivered via cesarean section were identified. Ninety-six women had cesarean section without myomectomy, and 65 women underwent cesarean myomectomy. We compared the maternal characteristics, neonatal weight, myoma types, and operative outcomes bet...

Background: Anemia is a global public health problem all around the world, principally developing countries like Nepal. results in maternal mortality alongside low birth weight which contributes to an increased infant rate. The prevalence of anemia ranges from 27% 42% among pregnant women depending on geographical regions. Iron and folic acid tablets are supplied free charge as part Nepal gover...

Background Child malnutrition during the first 1,000 days, commencing at conception, can have lifetime consequences. This study assesses the prevalence of anemia and undernutrition among children aged 6-23 months in midland and lowland agroecological zones of rural Ethiopia. Methods Cross-sectional data examining sociodemographic, anthropometry, hemoglobin levels, and meal frequency indicator...

During pregnancy, lower levels of maternal glucose before and during a glucose load have been associated with reduced infant birth weight and an increased risk of small-for-gestational-age births. A lower incremental area under the glucose response curve defines a low glycemic diet. Thus, during pregnancy the maternal diet, as measured by the glycemic index, may influence fetal growth and infan...