background: men, much like women, are faced with age-related menopause-like symptoms as they age. in recent years, increasing attention has been drawn to clinical research into elderly men and their health-related quality of life. the aging male scales (ams) questionnaire is an international tool for assessing the health-related quality of life in elderly men. hence far this questionnaire has n...

Fibroblasts organize the modular cell-adhesive glycoprotein fibronectin into a highly structured pericellular matrix by poorly understood mechanisms. Previous studies implicated an amino-terminal domain in matrix assembly and suggested that fibronectin's cell-adhesive domain and the corresponding fibroblast receptor were not involved in this process. To further elucidate the fibronectin region(...

During the inflammatory response, the adhesion molecule PECAM plays a crucial role in transendothelial migration, the passage of leukocytes across endothelium. We report here an additional role for PECAM in the subsequent migration of monocytes through the subendothelial extracellular matrix. PECAM has six immunoglobulin (Ig) superfamily domains. Monoclonal antibodies whose epitopes map to doma...

The vertebrate egg coat, including mammalian zona pellucida, is an oocyte-specific extracellular matrix comprising two to six zona pellucida (ZP) glycoproteins. The egg coat plays important roles in fertilization, especially in species-specific interactions with sperm to induce the sperm acrosome reaction and to form the block to polyspermy. It is suggested that the physiological functions of t...

Abstract In this article, we investigate the classification of self-adjoint boundary conditions odd-order differential operators. We obtain that for under some assumptions, there are exactly two basic types conditions: coupled and mixed. Moreover determine number possible each type, which is different from even-order cases. Our construction will play an important role in canonical forms spectra...