This study assessed age-related changes in power and heart rate in 114 competitive male cyclists age 15-73 years. Participants completed a maximal Kingcycle ergometer test with maximal ramped minute power (RMPmax, W) recorded as the highest average power during any 60 s and maximal heart rate (HRmax, beats/min) as the highest value during the test. From age 15 to 29 (n = 38) RMPmax increased by...

BACKGROUND In patients with congestive heart failure, the chronotropic and inotropic responses to beta-adrenergic agonists are reduced. It is not known whether desensitization of peripheral beta-adrenoceptors accounts for impaired limb vasodilation in these patients. Accordingly, we studied 14 normal subjects and 13 age-matched patients with congestive heart failure. METHODS AND RESULTS To di...

The maximal rate of progression of ST segment depression relative to increases in heart rate (maximal ST/HR slope) has recently been shown to be an accurate index of the presence and the severity of coronary heart disease in patients with angina. The value of this new exercise test was assessed in patients undergoing aortocoronary bypass. The maximal ST/HR slope and the results of coronary angi...

This study presents the results of maximal treadmill testing and cardiac catheterization in 40 asymptomatic and apparently healthy men with acquired right bundlebranch block. Eight of the men had significant anglographic coronary artery disease, and six of the eight only had single-vessel disease. The 40 men had normal maximal oxygen consumptions, normal maximal heart rates, and normal maximal ...

We investigated maximal Prym varieties on finite fields by attaining their upper bounds on the number of rational points. This concept gave us a motivation for defining a generalized definition of maximal curves i.e. maximal morphisms. By MAGMA, we give some non-trivial examples of maximal morphisms that results in non-trivial examples of maximal Prym varieties.

We used intraneural recordings of sympathetic nerve activity in conscious humans to determine if central command increases sympathetic discharge to resting skeletal muscle during static exercise. In nine healthy subjects, we measured arterial pressure, heart rate, and muscle sympathetic nerve activity with microelectrodes in the peroneal nerve of the resting leg during 1) static handgrip at 15%...

Spinal cord injury leads to a pronounced reduction of cardiovascular, pulmonary, and metabolic ability. Physical activity, up to and including high-performance sports, has obtained importance in the course of rehabilitation and the postclinical phase. Thirteen elite female wheelchair basketball players from the German National Basketball Team and 10 female sedentary spinal cord-injured persons ...

Sera from 20 patients with suspected or known coronary artery disease were measured for thyroxine (T4), tri-iodothyronine (T3), tri-iodothyronine uptake ratio (T3UR), thyroid stimulating hormone (TSH), and reverse tri-iodothyronine (rT3), before and after maximal or near-maximal exercise. On the average the patients achieved 92% (rang 68-108) of the predicted maximum heart rate. There were no s...

OBJECTIVE To examine the safety and effectiveness of cardiac rehabilitation on patients resuscitated from cardiac arrest due to acute myocardial infarction. METHODS The study included 23 subjects, including 8 with history of cardiac arrest and 15 without history of cardiac arrest. Both groups underwent initial graded exercise test (GXT) and subsequent cardiac rehabilitation for 6 weeks. After...

AIMS Benefit from exercise training in heart failure has mainly been shown in men with ischaemic disease. We aimed to examine the effects of exercise training in heart failure patients < or = 75 years old of both sexes and with various aetiology. METHODS AND RESULTS Fifty-four patients with stable mild-to-moderate heart failure were randomized to exercise or control, and 49 completed the stud...