This paper presents a multipole analysis of the QRS complex of the normal magnetocardiogram (MCG) of six normal subjects. The multipole strengths up to the octupole term were determined from the measured distribution of the z-component of the cardiac magnetic field (the component perpendicular to the frontal plane). This equivalent magnetic multipole generator was found to represent the cardiac...

This 29-year-old woman had transient episodes of palpitations, dizziness, diaphoresis, and nausea without provocation for several years. There was no history of hypertension. During induction of anesthesia for an orthopedic procedure, blood pressure (BP) suddenly increased from 122/76 mm Hg to 200/130 mm Hg and heart rate increased from 76 bpm to 108 bpm. Surgery was cancelled for a medical eva...

Butopamine is chemically similar to dobutamine but, unlike dobutamine, it is not a catecholamine. Preclinical studies on dogs show that butopamine is inotropic intravenously and orally. We gave butopamine intravenously to eight patients with congestive heart failure using a progressive dose-response protocol ranging from 0.02 to 0.17 mcg/kg/min. The mean cardiac index and stroke volume index in...

Cardiac sympathetic denervation (CSD) is reported to reduce the burden of ventricular tachyarrhythmias [ventricular tachycardia (VT)/ventricular fibrillation (VF)] in cardiomyopathy patients, but the mechanisms behind this benefit are unknown. In addition, the relative contribution to cardiac innervation of the middle cervical ganglion (MCG), which may contain cardiac neurons and is not removed...

MCG, the Multifunction Cardiogram, is a revolutionary approach to diagnosing cardiac conditions. It goes beyond a traditional ECG by incorporating aspects of computational biology and systems theory to build a functional mathematical model of the cardiac system – the heart, blood and circulatory system – from which a more accurate diagnosis can be drawn. This white paper discusses the theoretic...

Electrocardiogram (ECG) and magnetocardiogram (MCG) signals are among the most considerable sources of noise for other biomedical signals. In some recent works, a Bayesian filtering framework has been proposed for denoising the ECG signals. In this paper, it is shown that this framework may be effectively used for removing cardiac contaminants such as the ECG, MCG and ballistocardiographic arti...

We propose an automatic system for the classification of coronary artery disease (CAD) based on entropy measures of MCG recordings. Ten patients with coronary artery narrowing ≥ or ≤ 50% were categorized by a multilayer perceptron (MLP) neural network based on Linear Discriminant Analysis (LDA). Best results were obtained with MCG at rest: 99% sensitivity, 97% specificity, 98% accuracy, 96% and...

This study was conducted in 2006 to assess the current iodine nutriure of the population in Haryana by assessing the urinary iodine excretion levels amongst the school age children between 6-12 years. Altogether 3,019 urine samples were collected from all the 19 districts in Haryana. The urinary iodine was analyzed by using wet digestion method. Less than 1 % of children had urinary iodine excr...

BACKGROUND Vancomycin during continuous venovenous hemofiltration (CVVH) is either administered by intermittent infusion (II) or continuous infusion (CI). In this patient population, the best method to rapidly achieve target serum concentrations of 15 mcg/ml to 25 mcg/ml remains to be elucidated. We hypothesized that CI would achieve a target serum level of 15 mcg/ml to 25 mcg/ml within 24 h of...