نتایج جستجو برای: mechanotransduction
تعداد نتایج: 2457 فیلتر نتایج به سال:
OBJECTIVE Matrix-induced autologous chondrocyte implantation (ACI) offers a potential solution for cartilage repair but is currently hindered by loss of the chondrocyte differentiated phenotype. To further our understanding of the mechanism of dedifferentiation, changes in the phenotype in relation to mechanotransduction were recorded in response to monolayer culture. METHODS Bovine cartilage...
The guinea pig rectum, but not the colon, is innervated by a specialized class of distension-sensitive mechanoreceptors that have transduction sites corresponding to rectal intraganglionic laminar endings (rIGLEs). Rectal mechanoreceptors recorded in vitro had low threshold to circumferential stretch, adapted slowly, and could respond within 2 ms to mechanical stimulation by a piezo-electric pr...
Magnetomechanical Transduction In article number 2101826 by Rafael Morales, Gabriela Romero, and co-workers, magnetic microdiscs fabricated litography techniques are utilized to magnetically induce mechanotransduction in primary neural cultures. The red blue colors the indicate a component of special spin configuration known as vortex state.
The tip link protein protocadherin 15 (PCDH15) is a central component of the mechanotransduction complex in auditory and vestibular hair cells. PCDH15 is hypothesized to relay external forces to the mechanically gated channel located near its cytoplasmic C terminus. How PCDH15 is coupled to the transduction machinery is not clear. Using a membrane-based two-hybrid screen to identify proteins th...
Approved: ______________________________________________________ Dr. Joseph McGuire Hemodynamic forces regulate vascular homeostasis and arterial structure through mechanical stimuli by a process called mechanotransduction. Cellular response to mechanical forces involves coordination between cell surface receptors and intracellular signaling pathways. While previous work has focused on the role...
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