نتایج جستجو برای: medicinal chemistry
تعداد نتایج: 143302 فیلتر نتایج به سال:
Medicinal chemistry is an interdisciplinary science at the intersection of organic chemistry, biochemistry (bioorganic chemistry), computational chemistry, pharmacology, pharmacognosy, molecular biology, and physical chemistry. This branch of chemistry is involved with the identifi cation, design, synthesis, and development of new drugs that are safe and suitable for therapeutic use in humans a...
This special Symposium-in-Print issue of Bioorganic & Medicinal Chemistry Letters commemorates the 2008 Tetrahedron Young Investigator Award in Bioorganic & Medicinal Chemistry awarded to Benjamin F. Cravatt. Benjamin F. Cravatt is the Norton B Gilula Professor of Chemical Biology at The Scripps Research Institute. He received a B.S. degree in biological sciences and B.A. degree in history from...
The carbamate group is a key structural motif in many approved drugs and prodrugs. There is an increasing use of carbamates in medicinal chemistry and many derivatives are specifically designed to make drug-target interactions through their carbamate moiety. In this Perspective, we present properties and stabilities of carbamates, reagents and chemical methodologies for the synthesis of carbama...
1 Medicinal Chemistry, Louvain Drug Research Institute, Université catholique de Louvain. 73, Bte B1.73.10, Av. E. Mounier B-1200 Bruxelles, Belgium. 2 Unité de Formation et de Recherches en Pharmacie, Faculté des Sciences de la Santé, Université d’AbomeyCalavi, BP-188, Cotonou, Bénin. 3 Laboratoire de Pharmacognosie/UAC/CBRST ; Porto-Novo, BP 06 Oganla, Benin. 4 Medicinal Chemistry, School of ...
The novel selective D1 dopaminergic full agonists A-68930, A-77636 were discovered by the synthesis of molecules to probe the bioactive conformation of the partial agonist SKF-38393, by the use of this information to add D1 affinity and selectivity to a screening hit, and by traditional medicinal chemistry exploration of structure-activity relationships. The subsequent design of A-86929 and ABT...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید