ناآ دقل رهوج ،ةيفخ ةفصب تامولعملا لاسرإ و لاصتلاا عوضوم مدقلا ذنم مامتهلاا و ديعب نمز ذنم عساو لكشب مدختست ةيصنلا قئاثولا تناآ ، صوصنلا يف تامولعملا ءافخلإ ةفلتخم اًقرط مويلا ىتح نمز ذنم دهشن نحن كلذل ) Text Steganography .( لاقملا اذه نإ ط لوانتي ةيبرعلا و ةيسرافلا صوصنلا يف تامولعملا ءافخلإ ةديدج ةقير . و دوآ ينويلا ةفصاوم يف دجوي ) Unicode ( ءايلا فرحل نافلتخم نازمر » ى « ، فاكلا فرحل كلذآو...

هديكچ ط ي لاس اه ي خا ي ر پ ي تفرش لباق هظحلام ا ي رد طابترا اب لولس ه ا ي نب ي دا ي لصاح هدش تسا هک ون ي د شخب هار اهراک ي ون ي ن نامرد ي رد ب ي رام ي اه ي بعص جلاعلا م ي .دشاب ا ي ن لولس اه هک رد مامت ناگرا ي مس اه ي دنچ لولس ي روضح ،دنراد اناوت يي سقت ي م و دبت ي ل هب لولس اه يي سب ي را صاصتخا ي ار هتشاد و نچمه ي ن رداق هب اج ي زگ ي ن ...

صخلملا A total of 48 fresh water fishes, belonging to four species of the family Cyprinidae (Capoeta trutta, Chalcalburnus mossulensis, Cyprinion macrostomum and Leuciscus lepidus) were collected from Darbandikhan lake, southwest Sulaimaniya city, Kurdistan region, in the north of Iraq, from March to the end of July 2008. The inspection of gills revealed the infection of these fishes with four ...

ش ي ر ي ن ي فسو ي نا 1 (M.Sc) ، س ي د ما ي د انعر يي س ي تدا 1 (Ph.D) ، ونهد ناسحا ي 1 و 2 (Ph.D) ، قتدمحم ي جرب ي نا ـنجورب ي 1 (M.Sc) زاـنرف ن ي دازك نانمج ي 1 و 3 (M.Sc) 1 هاگشناد هش ي د تشهب ي ، هدكشناد ي سدنهم ي ژرنا ي روانف و ي اه ي ون ي ،ن امزآ ي هاگش بونان ي ژولونكتو ي ، ب هورگ ي ژولونكتو ي 2 هاگشناد برت ي ت هدكشناد ،سردم ي ز مولع ي تس ي 3 هاگشناد ملا...

We have recently shown that in vivo inhibition of histone deacetylase (HDAC) stimulates endogenous myocardial regeneration in infarcted hearts (Zhang L et al. J Pharmacol Exp Ther 341: 285-293, 2012). Furthermore, our observation demonstrates that HDAC inhibition promotes cardiogenesis, which is associated with HDAC4 reduction. However, it remains unknown as to whether specific inhibition of HD...

Porcine skeletal muscle fibres are classified based on their different physiological and biochemical properties. Muscle fibre phenotype is regulated by several independent signalling pathways, including the mitogen-activated protein kinase (MAPK), nuclear factor of activated T cells (NFAT), myocyte enhancer factor 2 (MEF2) and peroxisome proliferator-activated receptor (PPAR) signalling pathway...

Histone deacetylases (HDACs) have been shown to play important roles in the regulation of chromatin remodeling by histone deacetylation, and their expression is induced in several types of cancer. In addition, they are known to be associated with resistance to anticancer drugs. However, the relevance of HDAC4 in chemoresistance remains unclear. Therefore, we investigated the interaction between...

Acetylation or deacetylation of chromatin proteins and transcription factors is part of a complex signaling system that is involved in the control of neurological disorders. Recent studies have demonstrated that histone deacetylases (HDACs) exert protective effects in attenuating neuronal injury after ischemic insults. Class IIa HDAC4 is highly expressed in the brain, and neuronal activity depe...

Neural activity actively regulates muscle gene expression. This regulation is crucial for specifying muscle functionality and synaptic protein expression. How neural activity is relayed into nuclei and connected to the muscle transcriptional machinery, however, is not known. Here we identify the histone deacetylase HDAC4 as the critical linker connecting neural activity to muscle transcription....

Myocyte enhancer factor 2 (MEF2) has been implicated in the complex hierarchical regulation of muscle-specific gene expression and differentiation. While the MyoD family members are able to initiate the skeletal muscle differentiation program, whether MEF2 is sufficient in directing skeletal muscle differentiation is still controversial. Furthermore, how MEF2 transactivates its target genes is ...