Alzheimer’s disease (AD) is a chronic neurodegenerative disease causing progressive impairment of memory and cognitive function. Streptozotocin (STZ) injection into the brain is known to cause cognitive impairment in rats and is similar to sporadic AD in humans. Several lines of evidence have indicated that an inflammatory process contributes to the pathology of AD. On the basis of the results ...

Alzheimer’s disease (AD) is a chronic neurodegenerative disease causing progressive impairment of memory and cognitive function. Streptozotocin (STZ) injection into the brain is known to cause cognitive impairment in rats and is similar to sporadic AD in humans. Several lines of evidence have indicated that an inflammatory process contributes to the pathology of AD. On the basis of the results ...

Water intoxication causes hyponatraemia, which is responsible for the neurological dysfunction by causing intracellular overhydration. Symptoms may occur if the serum sodium concentration is less than 120 mmol/l, but the degree of brain dysfunction corresponds with the rapidity of development of the hyponatraemia. Intracellular potassium concentration is reduced, partly due to increased intrace...

Background: Premenstrual syndrome is a cyclic disorder with symptoms that are severe enough to interfere some aspect of living. The debilitating reappear each cycle, the most common being generalized headache, breast swelling and tenderness, bloating, fatigue, depression irritability. Aim: To determine efficacy mefenamic acid in treatment premenstrual women reproductive age groups. Methods: A q...

In the title compound, [Sn(C(6)H(11))(3)(C(15)H(14)NO(2))], the Sn(IV) atom adopts a distorted tetra-hedral SnOC(3) arrangement. The dihedral angle between the benzene rings in the mefanamic acid mol-ecule is 82.16 (17)° and intra-molecular N-H⋯O and C-H⋯O hydrogen bonds help to establish the conformation. Two of the cyclo-hexyl rings are disordered over two sets of sites with equal occupancies.