BACKGROUND In a major clinical trial, caspofungin was as efficacious as liposomal amphotericin B (LAmB) for empirical therapy in febrile neutropenia. The current study sought to evaluate the economic impact of caspofungin as compared with LAmB for febrile neutropenia in Australia. METHODS A decision analytic model was developed to capture the downstream consequences of the empirical antifunga...

Data from the Montana State University Targhee flock were used to estimate genetic and environmental relationships between lamb BW and adult ewe BW, condition score, and prolificacy. The flock was managed under commercial western range conditions typical of the area. Data included records from 12,154 lambs born to 2,930 dams and 200 rams between 1960 and 2005. Lamb traits included BW at birth a...

Overexpression of OmpC protein from an inducible plasmid vector reduced the amount of the precursor form of LamB protein in LamB signal sequence mutants. The stability of the precursor form of LamB protein was not affected, indicating that the effect of OmpC overexpression was on the synthesis of the precursor rather than on degradation. These results indicate that a functional signal sequence ...

What is the survival probability of a diffusing lamb which is hunted by N hungry lions? Although this capture process is appealingly simple to define ~see Fig. 1!, its long-time behavior poses a theoretical challenge because of the delicate interplay between the positions of the lamb and the closest lion. This model also illustrates a general feature of nonequilibrium statistical mechanics: lif...

effects of lamb and parents coefficient of inbreeding (ci) on wool weight were studied using 10,868 wool records belonging to 3,244 iran black lambs (1,633 males and 1,611 females) representing 96 rams and 995 ewes collected during 1983-2006 from animal breeding station of abbas abad. year and month of shearing, ci of lamb and dam, sex and birth type had significant affect on wool weight among ...

Disseminated aspergillosis is responsible for a high mortality rate, despite the use of antifungal drugs. Adjuvant therapies are urgently needed to improve the outcome. The aim of this study was to demonstrate that the cytoprotective effect of erythropoietin (EPO) combined with amphotericin B can reduce the mortality rate in a murine model of disseminated aspergillosis. After infection with Asp...

Nondestructive evaluation (NDE) of aerospace structures using traditional methods is a complex, time-consuming process critical to maintaining mission readiness and flight safety. Limited access to corrosion-prone structure and the restricted applicability of available NDE techniques for the detection of hidden corrosion or other damage often compound the challenge. In this paper we discuss our...

to investigate the relationship between chemical composition of meat from the carcass cuts and thewhole carcass, 48 nine-month-old randomly selected ram lambs of ghezel and mehraban (24 rams per breed)were used in a trial arranged as a 2 × 2 factorial experiment with two breeds and two feeding levels (high andlow), in a completely randomized design. after 80 days, all animals were slaughtered a...