The nanoporous metal-organic framework Fe2(azpy)4(NCS)4.(guest) (azpy is trans-4,4'-azopyridine) displays reversible uptake and release of guest molecules and contains electronic switching centers that are sensitive to the nature of the sorbed guests. The switching of this material arises from the presence of iron(II) spin crossover centers within the framework lattice, the sorbed phases underg...

* The opinions and information in this paper are those of the authors and do not represent the views and/or policies of the United States Food and Drug Administration. 1.1 Absorption, distribution, metabolism and excretion of melamine (MEL) 1.1.1 Rats MEL is rapidly absorbed and attains maximal plasma concentrations in 60 min following administration of a single oral dose to male Fischer 344 ra...

The hexaanion of mellitic acid, mel = (C(6)(CO(2))(6))(6-), links metal ions into extensively connected magnetic coordination polymers. Reaction of alkali metal mellitate salts, M(6)(mel) (M = K, Rb), with M'Cl(2) precursors (M' = Mn, Co, Ni) under mild (473 K) hydrothermal conditions yields an extensive family of isostructural 3-dimensional mixed alkali metal/transition metal polymers of gener...

Monte Carlo simulations and tight-binding calculations shed light on the properties of three-dimensional nanographene, a material composed of interlinked, covalently-bonded nanoplatelet graphene units. By constructing realistic model networks of nanographene, we study its structure, mechanical stability, and optoelectronic properties. We find that the material is nanoporous with high specific s...

In humans, the pineal hormone melatonin (MEL) is principally metabolized to 6-hydroxymelatonin (6-HMEL), which is further conjugated with sulfate and excreted in urine. MEL O-demethylation represents a minor reaction. The exact role of individual human cytochromes P450 (P450s) in these pathways has not been established. We used a panel of 11 recombinant human P450 isozymes to investigate for th...

Devices using electroactive polymer-supported carbon material can be exploited as alternatives to conventional electromechanical actuators in applications where electromechanical actuators have some serious deficiencies. One of the numerous examples is precise microactuators. In this paper, we show for first time the dilatometric effect in nanocomposite material actuators containing carbide-der...

Dendritic cells (DCs) phagocytose apoptotic influenza-infected monocytes and cross-present influenza antigen to CD8+ T cells, generating a specific CTL response. We investigated whether apoptotic melanoma cells, presented by this mechanism, can lead to CTL responses to tumor-associated antigens and melanoma cells. Apoptotic HLA-A2- MEL-397 melanoma cells were internalized by HLA-A2+ immature mo...