Background and aim: Melasma is an acquired, symmetric hyperpigmentation, specially in sun-exposed skin. Disorders of thyroid gland result from processes that stimulate the overproduction or underproduction of thyroid hormones. This study was performed to assess the association of melasma with thyroid disorders.Materials and Methods: This case-control study was performed...

ABSTRACT Background: Melasma, a common dermatological problem which has no standard recommended therapy. This study aimed to compare the clinical efficacy of combined trichloroacetic acid peel and ascorbic with alone in epidermal melasma. Methods: A quasi-experimental was conducted on 148 patients melasma, dermatology department Pak Emirates Military Hospital, Rawalpindi from August 2019 Januar...

BACKGROUND Melasma is an acquired disorder of hypermelanosis of great psychosocial concern. The treatments with various conventional therapies are often unsatisfactory. Lasers and light sources have been used to treat pigmented lesions, but in Asian skin with higher melanin content, such treatments may be challenging. OBJECTIVES To determine the effectiveness of treating melasma with a combin...

Melasma is an acquired symmetric hypermelanosis characterized by irregular light-to gray-brown macules and patches on sun-exposed areas. Many therapeutic agents are available but are unsatisfactory. Recently, it has been demonstrated that lincomycin (LM) and linoleic acid (LA) can inhibit melanogenesis in vitro. Our purpose was to investigate the clinical efficacy of topical application of LM a...

Melasma is a common disorder affecting a significant percentage of the population, particularly those with skin of color. Therapy with hydroquinone, a depigmenting agent, as a single agent or in combination with other agents has been used with variable success. A triple-combination (TC) cream combining hydroquinone 4% with tretinoin 0.05% and fluocinolone acetonide 0.01% was developed for the t...

OBJECTIVE To compare the efficacy and safety of Jessner's solution with 30% salicylic acid as superficial chemical peeling agents in treating epidermal melasma in Asian skin. STUDY DESIGN Double blind, randomized, interventional comparative study. PLACE AND DURATION OF STUDY Department of Dermatology, Combined Military Hospital, Malir Cantt, Karachi, from January to December 2004. PATIENT...

Introduction: Melasma is main cause of facial hyperchromia and has a significant psychosocial impact. Wood’s lamp been useful device to estimate the depth melanin determined by light-induced fluorescence. A dermoscope enables clear visualization pigments distribution, color variation will depend on its location within skin. Methods: cross-sectional observational study was conducted at outpatien...

Fractional resurfacing may be used in the management of melasma, striae/stretch marks, acne scars, pearly penile papule, syringoma, burn scar, verrucous epidermal naevus and skin tightening. In 20-30% of the patients with melasma, fractional resurfacing may not be effective or may even cause an exacerbation. Treatment effects may also be temporary. When compared with traditional carbon dioxide ...

Melasma is a pigmentary disorder that is characterized by poorly defined, dark brown macules on sun exposed areas, such as the face, back, and arms. This hyperpigmentation condition affects millions of people worldwide, the majority of whom are women. In the United States alone, it is estimated to affect over 6 million people, including up to 40% of the US female population1. Melasma is more pr...