BACKGROUND Vibrio vulnificus necrotizing skin and soft tissue infections (VNSSTIs) usually predispose patients with or without preexisting liver disease to septic shock, and then evolve to multiple organ dysfunction syndrome (MODS), thus resulting in high mortality in humans. However, clinicians do not have a valid prediction model to provide a reliable estimate of case-fatality rate when carin...

The proportion of patients undergoing liver transplantation (LT), with concomitant renal dysfunction, markedly increased after allocation by the model for end-stage liver disease (MELD) score was introduced. We examined the incidence of subsequent post-LT end-stage renal disease (ESRD) before and after the policy was implemented. Data on all adult deceased donor LT recipients between April 27, ...

We implement and prove correct binomial heaps and skew binomial heaps. Both are data-structures for priority queues. While binomial heaps have logarithmic findMin, deleteMin, insert, and meld operations, skew binomial heaps have constant time findMin, insert, and meld operations, and only the deleteMin-operation is logarithmic. This is achieved by using skew links to avoid cascading linking on ...

AIM To investigate whether the short-term prognosis of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) could be improved by using a modified model for end-stage liver disease (MELD) including serum lactate. METHODS This clinical study was conducted at the First Affiliated Hospital, Fujian Medicine University, China. From 2009 to 2015, 236 patients diagnosed with HBV-rela...

Introduction: The Child-Pugh (CP) score has long been used in predicting mortality in acute variceal bleeding. The model of end-stage liver disease (MELD) score was originally determined to predict survival in cirrhotic patients undergoing surgery. It is now used to assign priority for liver transplantation. MELD score is a useful tool to assess prognosis in critically ill cirrhotic patients. T...

Introduction: The model for end stage liver disease (MELD), disease-sodium (MELD Na), and Child-Turcotte-Pugh (CTP) score are independent predictors of mortality in cirrhotic patients. Approximately 43% patients with advanced frail can have detrimental effects on the prognosis survival including delisting from transplant list increased risk post-transplant complications. Therefore, our aim was ...

The laboratory-based model for end-stage liver disease (MELD) score reflects the function of the kidney, liver, and extrinsic coagulation pathway and might be used as a general prognostic tool for the assessment of patients. We therefore aimed to investigate a potential association of the MELD score with mortality, length of hospital stay (LOS), and disease burden in a general patient populatio...

Access to liver transplantation is reportedly inequitable for racial/ethnic minorities, but inadequate adjustments for geography and disease progression preclude any meaningful conclusions. We aimed to evaluate the association between candidate race/ethnicity and liver transplant rates after thorough adjustments for these factors and to determine how uniform racial/ethnic disparities were acros...

Endoscopic retrograde cholangiopancreatography (ERCP) is challenging in cirrhotic patients with choledocholithiasis. We evaluated the safety and efficacy of ERCP in cirrhotic patients with choledocholithiasis and accessed the model for end-stage liver disease (MELD) scores and Child-Pugh classifications for prediction of morbidity and mortality.From January 2000 to June 2014, 77 ERCP operations...

BACKGROUND & AIMS The current organ allocation system for liver transplantation (LT) creates an imbalance between patients with and without hepatocellular carcinoma (HCC). We describe a model designed to re-establish allocation equity among patient groups using transplant benefit as the common endpoint. METHODS We enrolled consecutive adult patients entering the waiting list (WL group, n=2697...