background: despite considerable investment in research, the existing research evidence is frequently not implemented and/or leads to useless or detrimental care in healthcare. the knowledge‑practice gap proposed as one of the main causes of not achieving the treatment goals in diabetes. iran also is facing a difference between the production and utilization of the knowledge of diabetes. the ai...

conclusions this investigation revealed that berberis fruit extract has beneficial metabolic effects in patients with type ii diabetes. barberry may improve glucose catabolism via glycolysis pathway, stimulate insulin secretion or improve insulin function and finally decrease glucose uptake. our results indicated that berberis fruit regulates glucose metabolism in patients with type 2 diabetes....

background: for decades, it was suspected that diabetes contributed to poorer oral health and the increased frequency of periodontitis. more recently it was found that periodontitis could adversely affect glycemic control in diabetics. the aim of this study was to compare periodontal parameters with the metabolic sugar levels of diabetic and non-diabetic individuals. materials and methods: in t...

background: health benefits of vitamin d has been proved by a large number of studies, however, to the best of our knowledge there has been no study investigating the effect of mega dose of vitamin d on gestational diabetes mellitus (gdm). this study was the first to assess the effect of postpartum injection of mega dose of vitamin d on blood pressure (bp) in gdm. methods: this is a randomized ...

the complex metabolic syndrome, diabetes mellitus, is a major human health concern in the world and is estimated to affect 300 million people by the year 2025. several drugs such as sulfonylureas and biguanides are presently available to reduce hyperglycemia in diabetes mellitus. these drugs have side effects and thus searching for a new class of compounds is essential to overcome this problems...

background: diabetes mellitus is a common metabolic disorder worldwide. it imposes excessive psychological stress on patients which negatively affect the course of the disease. the brain-behavioral systems have a role in dealing with stressful events such as chronic disorders. objective: comparison the brain-behavioral systems and psychological distress in diabetic patients and non-diabetics. m...

background: diabetes mellitus is the most common metabolic disorder with many complications such as neuropathic pain which relief from it is a dilemma. objectives: to investigate the effect of hydroethanolic extract of rubus fruticosus on neuropathic pain in diabetic rats. materials and methods: in this experimental case –control study, forty eight male wistar rats (250±20 g) were divided rando...

presence of maternal diabetes mellitus (dm) during pregnancy has important consequences for both mother and child. to determine maternal and fetal/neonatal complications of gestational dm and compare them with pre-gestational dm, a prospective study was performed in 100 diabetic women delivered in our hospital from january 2001 to april 2002. pregnancy outcome in 27 women with gestational dm an...

the clinical potentials of stem cells in cell-based therapies have raised great hopes in diabetes mellitus as well. however, there are complex ethical, legal, and socio-cultural issues surrounding the subject. in this paper, we intend to review in brief the main ethical issues for endocrinologists and other clinicians who are interested and work in the field of cell therapy and research.

epidemiology studies have demonstrated inconsistent associations between type 2 diabetes mellitus and the risk of malignant melanoma. to this end, the aim was to perform a meta-analysis of cohort studies.medline, pubmed, embase and the cochrane library were searched up to february 2014. cohort studies addressing the relative risk of type 2 diabetes mellitus on malignant melanoma were included i...