The understanding and management of membranous nephropathy, a common cause nephrotic syndrome that is more frequently encountered in adults than children, has rapidly evolved over the past decade. Identification target antigens allowed for precise molecular diagnoses, ability to monitor circulating autoantibodies added new vantage point terms disease monitoring decisions about immunosuppression...

Membranous nephropathy is one of the most common causes nephrotic syndrome. Among available treatment options, tried and tested regimen modified Ponticelli regimen. Despite adequate therapy, studies have shown that close to one-quarter patients fail attain complete remission. However, data limited regarding who are resistant this

Abstract Diabetic nephropathy (DN) is one of the most common microvascular diseases in diabetes. Primary membranous (PMN) causes nephrotic syndrome (NS) adults. Incidence DN and PMN are increasing. complicated with rarely reported. We report a case PMN. Early diagnosis very important, appropriate treatment can often achieve good results.

A 47-year-old woman developed pulmonary hemorrhage and an increase in proteinuria during remission of membranous nephropathy. Renal biopsy revealed crescentic glomerulonephritis. She also had a high perinuclear antineutrophil cytoplasmic antibody level, so a diagnosis of myeloperoxidase-antineutrophil cytoplasmic antibody-associated glomerulonephritis was made. After immunosuppressive therapy w...

Membranous nephropathy (MN) is the most common cause of the nephrotic syndrome in Europe, with an incidence of 5–10/million/year in adults [1]. Although MN can occur secondary to infections, systemic diseases, use of drugs or malignancies, in most patients no underlying cause is identified [idiopathic membranous nephropathy (iMN)]. Recent studies have identified antibodies against the M-type PL...

In a prospective survey of the nephritic syndrome due to primary renal disease in adult patients in the South-east Metropolitan Region of England 50 patients were seen in a two-year period-a minimum annual incidence of 9.0 new cases per million adult population. The frequency distribution of the three main histological groups was "minimal change" 30%, membranous nephropathy 12%, and proliferati...

We report a case of Kimura's disease with membranous nephropathy. A 15-year-old Japanese boy was referred to our hospital with proteinuria and a subcutaneous mass in the hip. Renal biopsy demonstrated secondary membranous nephropathy (MN) with mild mesangial proliferation and some electron-dense deposits in the mesangium. Laboratory tests revealed eosinophilia and a high level of serum IgE, whi...