BACKGROUND The ovary is an important site where gene variants modulate pubertal timing. The cannabinoid receptor 2 (CB2) is expressed in the ovary, plays a role in folliculogenesis and ovulation, and can be modulated by estrogens. Obesity is strictly associated with early menarche and is characterized by sex hormone and endocannabinoid derangement. AIM In this study, we investigated the role ...

INTRODUCTION Delayed pubertal maturation has been reported in girls with type 1 diabetes. OBJECTIVES To report the age of onset of puberty and menarche in girls with type 1 diabetes diagnosed before puberty. To investigate clinical factors affecting the occurrence of puberty and menarche in this population. PATIENTS AND METHODS A retrospective study of 38 girls with type 1 diabetes, all of ...

BACKGROUND Menarche is considered as a milestone in the women's reproductive life. Most existing studies on factors influencing menarcheal age had cross-sectional designs and their finding were controversial. OBJECTIVES We aimed to determine some factors affecting the age at menarche in a cohort study with an average of ten-year follow-up; the study was conducted within the framework of Tehra...

BACKGROUND A growing number of studies suggest a link between timing of menarche and risk of depressive symptoms in adolescence, but few have prospectively examined the emergence of depressive symptoms from late childhood into adolescence. AIMS To examine whether girls who experience earlier menarche than their peers have higher levels of depressive symptoms in adolescence. METHOD The study...

background: menarche, a milestone in the reproductive life span of a woman, is influenced by several genetics and environmental factors. there is no consensus regarding the impact of body mass index (bmi) and lipid profiles on the age of menarche, as the results of various studies demonstrate. objective: to investigate the correlation between age of menarche and bmi/lipoprotein profile in a com...

Aim: The objective of this study is to fill the information gap by providing detailed information on the development of girls’ BMI and hip and waist circumferences in correlation with their menarche status and to examine the impact of considering menarcheal age in addition to numerical age in the assessment of overweight and abdominal overweight. Subjects and Methods: The description of data is...

BACKGROUND While menarche indicates the beginning of a woman's reproductive life, relatively little is known about the association between age at menarche and subsequent morbidity and mortality. We aimed to examine the effect of lower age at menarche on all-cause mortality in older Australian women over 15 years of follow-up. METHODS Data were drawn from the Australian Longitudinal Study of A...

BACKGROUND Prediction of the onset of menstruation (menarche age) using height, weight and Body Mass Index (BMI) is a major health procedure. The present study was conducted to determine the relationship between anthropometric indices and menarche age in 488 girls 11-17 years in southern Iran (Kish Island) in 2011. METHODS Data was collected using questionnaires as well as measurements of the...

BACKGROUND While the timing of reproductive events varies across populations, a downward trend in age at menarche has nevertheless been reported in most of the developed world over the past century. Given the impact of change in age at menarche on health conditions, this study sought to examine secular trends in age at menarche among women living in Navarre (Northern Spain) who participated in ...

BACKGROUND Research shows that the age at menarche, as an essential element in the reproductive health of women, had been decreasing in the 19(th) and 20(th) centuries, and shows a huge variation across different countries. There are numerous studies performed in Iran reporting a range of age at menarche. Thus, this meta-analysis aimed to determine the overall mean age at menarche of the girls ...