An image processing algorithm is developed for quantitative assessment of tear meniscus dynamics from continuous optical coherence tomography (OCT) measurements. Clinical utility of dynamic OCT tear meniscus measurement is assessed in studies of tear meniscus parameters. The results indicate that any apparent changes in the early post-blink phase meniscus parameters are essentially related to t...

A ring-shaped lateral meniscus is an uncommon morphological variant, and its etiology remains unclear. A 38-year-old male was admitted to our institution complaining of right knee pain and locking. Magnetic resonance imaging suggested a bucket-handle tear in the medial meniscus and a discoid lateral meniscus. On arthroscopic evaluation, however, a ring-shaped lateral meniscus was detected in th...

background:  despite the introduction of different techniques for meniscal repair, no single procedure is superior in all situations. the new method for meniscal repair named “ modified outside-in technique ” aims to achieve higher primary fixation strength by an alternative suture technique as well as avoid disadvantages of outside-in, inside-out, and all-inside suture procedures. additionally...

Background: Meniscus allograft transplantation (MAT) may be indicated for young patients with joint line pain following subtotal or total meniscectomy. Several different approaches performing MAT have been described in the literature and are influenced by appropriate patient selection, graft-sizing, soft-tissue fixation techniques. Clinical studies demonstrate favorable results regarding relief...

BACKGROUND Lesions in the meniscus are risk factors for developing knee osteoarthritis (OA), not least because of the role of the meniscus in the pathological progression of OA. Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) has extensively been used to identify pre-radiographic cartilage changes in OA. In contrast, its counterpart with regard to examination of the meniscus, gadolinium ...

Meniscus integrity is the key for joint health of the knee. Therefore, the main goal of every meniscus treatment should be the maintenance of as much meniscus tissue as possible.Repair of meniscus tears can be achieved by meniscus suture. However, in a recently published meta-analysis, the long-term outcome of meniscus repair showed a mean failure rate of 24%.In a preclinical trial, locally app...

In previous work we demonstrated that the matrix-forming phenotype of cultured human cells from whole meniscus was enhanced by hypoxia (5% oxygen). Because the meniscus contains an inner region that is devoid of vasculature and an outer vascular region, here we investigate, by gene expression analysis, the separate responses of cells isolated from the inner and outer meniscus to lowered oxygen,...

Meniscus injuries remain a significant challenge due to the poor healing potential of the inner avascular zone. Following a series of studies and clinical trials, tissue engineering is considered a promising prospect for meniscus repair and regeneration. As one of the key factors in tissue engineering, cells are believed to be highly beneficial in generating bionic meniscus structures to replac...