نتایج جستجو برای: mesobuthu eupeus
تعداد نتایج: 132 فیلتر نتایج به سال:
سلولهای خونی شاخص مهم ایمنی بندپایان در برابر بیمارگرها و پارازیتوئیدها میباشند. با شناخت دقیق سلولهای خونی و واکنش آنها در برابر عوامل بیگانه ای که به همولنف وارد میشوند، بهتر میتوان جنبه های دفاع سلولی حشره را بررسی کرد. با توجه به تحقیقات بسیار اندک در بیولوژی عقربها در این تحقیق، سلولهای خونی مزوبوتوس اپئوس با استفاده از میکروسکوپ نوری مورد مطالعه قرار گرفت. پنج نوع هموسیت در عقرب مز...
Introduction: Scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (AMPs) have been found in the venom gland of scorpions. Therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. Here, we describe three new cationic AMPs, including meuVAP-6, meuAP-18-1, and meuPep34 from the ve...
background: meict is the first chlorotoxin-like peptide isolated from the iranian scorpion mesobuthus eupeus. chlorotoxin (ctx) is a neurotoxin that specially binds to (mmp-2) on ma-lignant cells and now is used in treatment of glioma. in the present study, we have used homology modeling to propose the 3d structure of meictand analyze its interaction with mmp-2 and its snp types. methods:the st...
Scorpion venom contains different toxins with multiple biological functions. IMe-AGAP is the first Analgesic-Antitumor like Peptide (AGAP) isolated from Iranian scorpion Mesobuthus eupeus. This peptide is similar to AGAP toxin with high analgesic activity, extracted from Chinese scorpion and inhibits NaV1.8 and NaV1.9 voltage-gated sodium channels involved in the ...
Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints as well as other organs in the body. Adjuvant-induced arthritis models in inbred rats serve as relevant models for RA, having many clinical similarities to this disease. Using honey bee venom as a treatment for Rheumatoid arthritis is an ancient therapy in various parts of the world. However scorpion ve...
background: scorpions’ stings and their own mortalities place them among the most important health and medical problems. the dreadful features and especially their poisonous stings are considered a major cause of human stress and abhorrence/phobia. the current study aimed to study the scorpion fauna of ilam province, south western iran in order to manage scorpionism related problems. methods: i...
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Introduction: Considering wide distribution of scorpions in various parts of the country and their importance in biological and medical Sciences, the current study was performed during 2005 to 2006 in order to determine scorpions species in Kerman/Iran. Method: In this descriptive research, 13 cities in Kerman province were investigated. All collected scorpion specimens in %75 ethyl alcohol wer...
Background: MeICT is the first chlorotoxin-like peptide isolated from the Iranian Scorpion Mesobuthus eupeus. Chlorotoxin (CTX) is a neurotoxin that specially binds to (MMP-2) on ma-lignant cells and now is used in treatment of glioma. In the present study, we have used homology modeling to propose the 3D structure of MeICTand analyze its interaction with MMP-2 and its SNP types. Methods:The ...
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