The immuno-pharmacological properties of ethanolic extract of Nyctanthes arbor-tristis Linn. (NA) have been investigated. After administration of Nyctanthes arbor-tristis in doses of 0.25 and 0.5 g/kg body weight (BW) a significant increase in phagocytic index, leukocyte count and spleenic antibody secreting cells were noticed. Stimulation of humoral immune response was further observed with he...

OBJECTIVE A number of studies have evaluated the association between flavonoids intake and lung cancer risk. However, results were inconsistent. To clarify the role of flavonoids in lung cancer, we conducted a meta-analysis on this topic. METHODS Two authors independently searched PubMed and EMBASE for studies regarding the association of flavonoids intake with lung cancer risk. Summary relat...

Recently new techniques to efficiently manage biological information of biology have played an important role in the area of information technology. The flavonoids are members of a class of natural compounds that recently has been the subject of considerable scientific and therapeutic interest. This paper presents a Grid-based flavonoids web portal system. We designed relational schema, XML sch...

The total flavonoids of Houttuynia cordata are determined by UV-Vis spectrophotometry. The extraction condition of flavonoids from Houttuynia cordata includes: the extraction temperature is 70 ̊C, solid-liquid ratio is 1:20, solvent is 80% ethanol, extraction time is 65 min. We studied the antioxidation of flavonoids in Houttuynia cordata, and results showed that flavonoids had strong reducing c...

Flavonoids (quercetin, rutin) influence ATPase activity and actomyosin superprecipitation. Low concentrations (below 20 mumol/l) of flavonoids were found to cause conformational changes in the myosin structure accompanied by an increase in ATPase activity. At higher concentrations an inhibitory action of flavonoids on both ATPase activity and actomyosin superprecipitation occurred. Conformation...

To investigate the effects of flavonoids on free radical-mediated biological membrane damage and the interaction of flavonoids with heme proteins, we studied the effects of quercetin, its glycosides (rutin and quercetin-3-O-glucoside), morin and (-)epicatechin on the hemolysis of the bovine erythrocytes induced by the hydrophilic free radical initiator, 2,2'-azobis(2-amidinopropane)dihydrochlor...

Flavonoids are crucial signaling molecules in the symbiosis between legumes and their nitrogen-fixing symbionts, the rhizobia. The primary function of flavonoids in the interaction is to induce transcription of the genes for biosynthesis of the rhizobial signaling molecules called Nod factors, which are perceived by the plant to allow symbiotic infection of the root. Many legumes produce specif...

Mycobacterium tuberculosis, an agent of tuberculosis (TB), causes serious health problems such as multi drug resistance (MDR-TB), and extensive drug resistance (XDR-TB). According to WHO, 490,000 cases of MDR-TB and 40,000 cases of XDR-TB occur every year. There are several reasons to investigate a new class of antimicrobial drugs and the flavonoids represent a novel set of possibilities. Flavo...