objective(s): with the advent of nanotechnology, significant progress has been made in the area of nanoscale materials such as nanosilver (ag-nps). these nanoparticles have a wide range of applications and been used for antimicrobial purposes for more than a century. however, little attention has been paid to the toxicity of nanosilver wound dressing. this study was designed to investigate the ...

P. vermicola is an opportunistic pathogen of human and animals. To estimate the pathogeneses P.vermicola in mice infected orally I/P with 1x108 CFU/ml).The histopathological changes at 24 hrs showed infiltration inflammatory cells apoptosis hepatocytes liver, around a congested blood vessel interstitial tissue kidney; lung revealed congestion vessels, alveolar emphysema; intestine appeared mono...

Objective(s): Liver transplantation is the most important therapy for end-stage liver disease and ischemia reperfusion (I/R) injury is indeed a risk factor for hepatic failure after grafting. The role of miRNAs in I/R is not completely understood. The aim of this study was to investigate the potential protective role of the mesenchymal stem cells (MSCs) and ischemic pr...

Pregnant normal (N) and acatalasemic (A) mice treated with aminotriazole (AT) were exposed to metallic mercury. The mercury contents of the fetus and maternal organs were subsequently determined. The fetal and placental mercury contents were the highest in the AT-treated A mice (A-AT), and the contents decreased in the order of AT-treated N mice (N-AT), non-treated N mice (N-C) and non-treated ...

Lactobacillus are considered promising therapeutic methods for nonalcoholic fatty liver disease (NAFLD). The effects of two strains Limosilactobacillus mucosae (L. mucosae) on NAFLD were investigated in this study. Four-week-old male C57BL/6J mice divided into four groups (n=8 per group, Control, Model, FZJTZ26M3, FGSYC17L3). FZJTZ26M3 reduced the mice's body weight, ...

Introduction: Rifampin is one of the common drugs used to treat tuberculosis and considered a strong toxic agent for liver. The aim this study investigate effects cinnamon extract administration on rifampin-induced hepatotoxicity in rats. Materials methods: In experimental study, 60 male Wistar rats were randomly divided into 6 groups. Liver damage induction oxidative stress caused by 80 mg/kg/...

This study analyzed the effects of 24 h cold stress (22°C or 5°C vs. mice maintained at 30 °C) on plasma, brown adipose tissue (BAT), subcutaneous (SubQ) and epididymal (Epi) white (WAT), liver, skeletal muscle lipidome mice. Using mass spectrometry-lipidomics, 624 lipid species were detected, which 239 significantly altered in 134 BAT, 51 liver. In acylcarnitines free fatty acids markedly incr...

objective(s) quinazolinones are heterocyclic compounds, with biological and pharmacological activities, such as inhibiting some proteins, enzymes and reducing blood lipids. materials and methods following previous results of our group, effects of two new derivatives of quinazolinones 9(3)-quinazolinone-2-propyl-2-phenylethyl (qppe) and 9(3)-quinazolinone-2-ethyl-2-phenylethyl (qepe) on livers, ...

The study was conducted on male mice (Albino mice), which ranged in age from (2-3) months and weights (25 - 30) g. experiment the General Company for manufacture of medicines medical supplies Samarra. And period beginning October 2017 to end March 2018, Used 42 animals were distributed seven groups, each containing 6 animals, determine effects both gannoderma spirulina laboratory induced by dia...

Purpose. To study suppressor and/or cytotoxic activity of the nuclear erythroid cells (NEC) against tumor various origins. Material and Methods. C57Bl/6 mice P815, L1210, B16 L929 were used. “Phenylhydrazine” NECs obtained from with induced hemolytic anemia. “Erythropoietin” isolated “phenylhydrazine spleen” further cultured in presence erythropoietin. Another source NEC was neonatal mouse sple...