A fluorescence-based method has been developed to detect the structural changes that occur in micelle systems. The sensitivity of fluorescein isothiocyanate (FITC) has been evaluated for (i) detecting the micellization of cetyltrimethyl ammonium bromide (CTAB) and (ii) probing the concentration dependent aggregation, leading to microstructural changes that occur within CTAB micelles. The critic...

Micelle-forming detergents provide an amphipathic environment that can mimic lipid bilayers and are important tools for solubilizing membrane proteins for functional and structural investigations in vitro. However, the formation of a soluble protein-detergent complex (PDC) currently relies on empirical screening of detergents, and a stable and functional PDC is often not obtained. To provide a ...

The unique rheological properties of viscoelastic wormlike micelle solutions have led to their broad use as rheological modifiers in consumer products such as paints, detergents, pharmaceuticals, lubricants and emulsifiers. In addition, micelle solutions have also become increasingly important in a wide range of industrial and commercial applications including agrochemical spraying, inkjet prin...

The mixed micellization between the nonionic surfactant decanoyl-N-methylglucamide (MEGA-10) and the common sodium dodecyl sulfate (SDS) in aqueous solutions of 0.1 M NaCl was investigated by the fluorescence probe method. The critical micelle concentrations were determined by the pyrene 1:3 ratio method. The experimental data are discussed in light of two mixing thermodynamic models within the...

We have examined the rate-limiting steps involved in bile acid absorption across the unstirred water layer and lipid cell membrane of the jejunal mucosa. Uptake of the polar bile acid taurocholate is limited solely by the cell membrane since this compound permeates the unstirred water layer more rapidly than the lipid cell membrane and stirring does not enhance uptake. With less polar bile acid...

Micro/nanoparticles could cause adverse effects on cardiovascular system and increase the risk for cardiovascular disease-related events. Nanoparticles prepared from poly(ethylene glycol) (PEG)-b-poly(ε-caprolactone) (PCL), namely PEG-b-PCL, a widely studied biodegradable copolymer, are promising carriers for the drug delivery systems. However, it is unknown whether polymeric PEG-b-PCL nano-mic...

Anisotropic nanoparticles prepared from block copolymers are of growing importance as building blocks for the creation of synthetic hierarchical materials. However, the assembly of these structural units is generally limited to the use of amphiphilic interactions. Here we report a simple, reversible coordination-driven hierarchical self-assembly strategy for the preparation of micron-scale fibr...

The conformational behaviors of charged brushes on a micelle self-assembled by charged-neutral diblock copolymers in salt-free solution are extensively analyzed using a coarse-grained dissipative particle dynamic (DPD) simulation. When only monovalent counterions exist, the brush conformation of the corona in the micelle is exactly consistent with the predictions from the blob-scaling theory ba...

The proton magnetic resonance spectrum of DL-a!-lecithin at 100 MHz in CHCJ solvent is reported. An analysis of the spectrum is made. The chemical shifts of the N-(CH& protons and the resonance peak associated with the condensed water molecule showed concentration dependence with the latter showing the more pronounced response. These chemical shift changes are interpreted in terms of micelle fo...