Breast cancer is a major cause of cancer deaths among women. Early detection plays an important role for improving breast cancer prognosis. Mammography is used to demonstrate the presence of breast cancer and to identify the size and location of tumor cells. Texture analysis refers to a procedure or a model that characterizes the spatial variation within the image by extracting information. In ...

BACKGROUND Recent studies suggest that uric acid is a mediator of diabetic nephropathy. We hypothesized that elevated serum uric acid levels are a strong predictor of albuminuria in patients with type 1 diabetes. METHODS We analyzed data from the Coronary Artery Calcification in Type 1 Diabetes study, a prospective observational study. A stepwise logistic regression model was applied to predi...

BACKGROUND Calcific aortic valve disease is the most common indication for surgical valve replacement in the United States. The cellular mechanisms of valve calcification are not well understood. We have previously shown that cellular proliferation and osteoblastogenesis are important in the development of valvular heart disease. Lrp5, a known low-density receptor-related protein, plays an esse...

statement of the problem: most of the soft tissue calcifications within the head and neck region might not be accompanied by clinical symptoms but may indicate some pathological conditions. purpose: the aim of this research was to determine the prevalence of soft tissue calcifications in cone beam computed tomography (cbct) images of mandibular region. materials and method: in this cross sectio...

INTRODUCTION: Clinical researchers lack convenient software tools to investigate mechanisms of bone fracture on a patient-specific basis. Such a tool must be user-friendly and, as bone mineral density alone fails to predict fracture, incorporate both macroand micro-structural information. Micro-parameters relevant to initiation, propagation and arrest of microcracks that cumulatively lead to fr...

objective(s): vascular calcification is one the major characteristics in patients with various types of chronic inflammatory disorders. mirnas have been shown to be involved in many normal biological functions as well as diseases; however, their role in vascular calcification has not received much attention. materials and methods: in the current study, we built a vascular calcification rat mode...