نتایج جستجو برای: microcarriers
تعداد نتایج: 377 فیلتر نتایج به سال:
Multicellular contact has been shown to influence the in vitro sensitivity of cells to drug treatment. We investigated the use of macroporous gelatin microcarriers, CultiSpher-G, as a convenient laboratory system for the molecular analysis of this "contact effect". We determined that human A549 cells can be grown in CultiSphers with growth and cell cycle parameters similar to those of monolayer...
We had previously demonstrated the feasibility of preparing a centimeter-sized bone tissue construct by following a modular approach. In the present study, the objectives were to evaluate osteogenesis and tissue formation of human amniotic mesenchymal stem cells-laden CultiSpher S microcarriers during in vitro perfusion culture and after subcutaneous implantation. Microtissues were prepared in ...
Definitive treatment to achieve wound healing in major burns frequently include skin transplantation, where split-thickness grafts is considered gold standard. This method associated with several drawbacks. To overcome these hurdles, efforts have been made develop tissue engineered substitutes, often comprised of a combination cells and biomaterials. In the present study, we aimed investigate t...
Biomimetically modified bioactive materials with bone-like surface properties are attractive candidates for use as microcarriers for 3-D bone-like tissue engineering under simulated microgravity conditions of NASAdesigned rotating wall vessel (RWV) bioreactors. The simulated microgravity environment is attainable under suitable parametric conditions of the RWV bioreactors. Ca-P containing bioac...
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