The reorganization of the macronucleus from the vegetative micronucleus is described in Epistylis articulata (Ciliophora, Peritricha). Individuals which have accidentally been deprived of a macronucleus during binary fission develop a new one from the micronucleus. In such amacronucleate animals, the micronucleus divides into two, one of them growing into a macronucleus, the other remaining as ...

Hypericum species, growing wild in Anatolia, widely used in traditional medicine in Turkey. In order to determine the genotoxic effect of Hypericum heterophyllum, human lymphocytes were incubated with the aqueous extracts. The increasing extract concentrations of Hypericum heterophyllum induced micronucleus. The rise of micronucleus shows that Hypericum heterophyllum at high concentrations may ...

Toxicity and genotoxicity tests were performed on root cells of Allium cepa in order to evaluate wastewater quality following an ECF cellulose bleaching process. The results revealed a toxic effect of the effluent, with inhibition of meristem growth and generally lower values of metaphase, anaphase and telophase indices at pH 10.5 than pH 7 for all effluent concentrations. The genotoxicity effe...

We studied the genotoxic potency of motorcycle exhaust particles (MEP) by using a bacterial reversion assay and chromosome aberration and micronucleus tests. In the bacterial reversion assay (Ames test), MEP concentration-dependently increased TA98, TA100, and TA102 revertants in the presence of metabolic-activating enzymes. In the chromosome aberration test, MEP concentration-dependently incre...

Pollutants have adverse effects on human health and on other organisms that inhabit or use water resources. The aim of the present study was to assess the environmental quality of three watercourses in Monte Carmelo, MG, Brazil, using the micronucleus test on Tradescantia. For each treatment, 15 plants were exposed to water samples for 24 h. The control group was exposed to formaldehyde (0.2%) ...

Air pollution is exacerbated near heavy traffic roads in cities. Air pollution concentration and composition vary by region and depend on urban-rural gradients. The aim of this study was to evaluate the distribution of air pollution in areas of varying population densities and to compare plant biomonitoring with an established biomarker of human exposure to traffic-related air pollution in chil...

The Semipalatinsk area is highly contaminated with radioactive fallout from 40 years of continuous nuclear testing. The biological effects on human health in this area have not been studied. Significant remaining radioactivities include long-lived radioisotopes of 238,239,400Pu, 137Cs and 90Sr. To evaluate the long-term biological effects of the radioactive fallout, the incidence of micronuclei...

In addition to their applicability as biopesticides, Bacillus thuringiensis (Bt) Cry1Ac spore-crystals are being researched in the immunology field for their potential as adjuvants in mucosal and parenteral immunizations. We aimed to investigate the hematotoxicity and genotoxicity of Bt spore-crystals genetically modified to express Cry1Ac individually, administered orally (p.o.) or with a sing...

Armen K. Nersesyan* Institute of Cancer Research, Medical University of Vienna, Vienna A-1090, Austria __________________________________________________________________________________ *Correspondence: Armen K. Nersesyan, Institute of Cancer Research, Medical University of Vienna, Vienna A-1090, Austria; Phone: +431 4277 65146; Fax: +431 4277 9651; E-mail: [email protected]; arm...

Lafoensia pacari (Lythraceae), popularly known in Brazil as "pacari", is a small tree native to the Cerrado that is used in folk medicine to treat cancer and as an anti-inflammatory and cicatrizing agent. We evaluated the genotoxic, cytotoxic, antigenotoxic, and anticytotoxic activities of an ethanol extract of L. pacari stem bark (EESB) using the Ames test and the mouse bone marrow micronucleu...