We present a case of 67-year-old male with end-stage renal disease (ESRD) on hemodialysis who was admitted to the hospital after recurrent falls secondary postural hypotension. He not able tolerate fluid removal dialysis due persistent hypotension despite maximal doses midodrine and developed severe edema. A right heart catheterization revealed raised biventricular filling pressure consistent f...

Abstract Funding Acknowledgements Type of funding sources: None. Background 8% the population suffer recurrent episodes syncope which can cause physical injury and psychological morbidity. The extent to therapeutic options effectively reduce recurrence beyond placebo remain unclear. Methods We performed a meta-analysis randomised trials including pharmacological, cardiac pacing interventions fo...

Postural tachycardia syndrome (POTS) is defined by a heart rate increment of 30 beats/min or more within 10 minutes of standing or head-up tilt in the absence of orthostatic hypotension; the standing heart rate is often 120 beats/min or higher. POTS manifests with symptoms of cerebral hypoperfusion and excessive sympathoexcitation. The pathophysiology of POTS is heterogeneous and includes impai...

Delayed ejaculation (DE) is an uncommon and a challenging disorder to treat. It is often quite concerning to patients and it can affect psychosocial well-being. Here we reviewed how DE is treated pharmacologically .We also highlighted specific settings where drugs could be introduced to medical practice. Electronic databases were searched from 1966 to February 2016, including PubMed MEDLINE, EM...