Allergy to cows' milk-protein is an occasional cause ofpersistent diarrhoea (Clein, 1954; Collins-Williams, 1954; Kane, 1957; Bachman and Dees, 1957a, b; Davies, 1958), but in the absence of other overt signs of allergy, may easily be overlooked. The management of milk intolerance often involves the use of synthetic feeds, which in themselves may produce a fulminating illness (Wilson and Clayto...

Objective: To determine transforming growth factor (TGF) β1, interleukin (IL) 4, and IL-10 concentrations in human milk and to assess the relationship between allergic disorders in mothers and the content of the interleukins in their milk. Material and methods: Thirty allergic and 46 healthy mothers were included in the study. Colostrum was collected 2–3 days after delivery. Cytokine concentrat...

OBJECTIVES Knowledge about the prevalence of allergies to foods in childhood and adolescence is incomplete. The purpose of this study was to investigate the prevalence of allergies to milk, egg, cod, and wheat using reported data, clinical examinations, and double-blind placebo-controlled food challenges, and to describe the phenotypes of reported food hypersensitivity in a cohort of Swedish sc...

Background Certain foods are used as excipients in pharmacological products. Thus, patients with lgE-mediated food allergy could present reaction to the pharmacological product whose the excipient is the food in question. Such reactions are rare, considering the small quantity of food protein present in the products. In most situations, these medicines need not be avoided in patients with food ...

AIM To evaluate the prevalence of parent-reported food allergies requiring avoidance diet at early school age. METHODS The school health nurses interviewed, by using a structured questionnaire on the required diet at school, the parents of all the 1542 children starting elementary school in a Finnish town with 210,000 inhabitants. RESULTS An allergy to basic foods was found in 41 (2.7%) chi...

Introduction Caseins cross-reactivity rises up to 90% between cow’s milk (CM) and other bovid milks. There are few studies on tolerance to other mammals milk in patients submitted to cow’s milk oral immunotherapy (CMOIT). AIMS: To determine the percentage of patients whom after CMOIT tolerate water buffalo (WB), goat and sheep’s milk proteins (MP). To describe immunologic features which can pre...

There is emerging evidence that children with egg and cow's milk allergy who can tolerate these allergens cooked in baked goods are more likely to develop tolerance. As a result a hypothesis has arisen that exposure to egg and milk in baked goods may hasten tolerance development; however, it is unclear whether children who develop tolerance do so because they have ingested low levels of egg or ...

Food allergy in children is increasing and the perception of food allergy among parents is even more common. In a questionnaire-based study of 702 children aged 6 to 48 months in four primary care settings, the aim was to determine the prevalence of perception vs. proven food allergy, parental anxiety and general pediatrician knowledge of food allergy. In 95/702 children (13.5%) parentally-repo...

A 10-day-old male neonate was admitted with bilious vomiting and gross hematochezia. Peripheral eosinophilia, delayed positive skin prick test to artificial milk, and elevated eosinophil cationic protein levels suggested cow's milk allergy. Fluid infusion with prohibition of oral intake improved the digestive symptoms. Breast-feeding was resumed on hospital day 3 and only casein hydrolysate for...

There are a large number of commercially available milk formulae labelled as “hypoallergenic”. However, only a minority of these comply with the criteria established in the guidelines of Subcommittee on Nutrition and Allergic Disease of the American Academy of Pediatrics. As far as the treatment of cow’s milk allergy is concerned, the extensive hydrolysed protein formulae and aminoacid-based fo...