Integrated PET/MRI systems open exciting possibilities for clinical and research applications. However, compared with PET/CT, PET/MRI is a complex technique resulting in new problems and challenges, especially regarding workflow, scan protocols, and data analysis. This complexity applies in particular to examinations in oncology with partial- or whole-body coverage extending over several bed po...

Multiple sclerosis (MS) refers to the lesions that accumulate in the brain and spinal cord. Magnetic resonance imaging (MRI) is the most sensitive and versatile modality used to show changes in the tissues over time. There has been significant interest in evaluating the relationship between the brain atrophy and disease progression rather than the spinal cord atrophy. The cervical spinal cord h...

Tumors are cells that grow abnormally and uncontrollably, whereas brain tumors growing in or near the brain. It is estimated 23,890 adults (13,590 males 10,300 females) United States 3,540 children under age of 15 would be diagnosed with a tumor. Meanwhile, there over 250 cases Indonesia patients afflicted tumors, both infants. The doctor medical personnel usually conducted radiological test co...

PURPOSE Validating deformable multimodality image registrations is challenging due to intrinsic differences in signal characteristics and their spatial intensity distributions. Evaluating multimodality registrations using these spatial intensity distributions is also complicated by the fact that these metrics are often employed in the registration optimization process. This work evaluates rigid...

Breast cancer is found to be the most common form of cancer found in women which is the leading cause for cancer death worldwide. Detection of abnormality at the earliest increases the chances of successful treatment and can reduce the mortality rate. MRI is a widely used medical imaging technique. Noise in MRI negatively affects image processing and analysis works. The main objective of prepro...

AIM Evaluate the diagnostic accuracy of 68Ga-labeled HBED-CC-PSMA-PET/MRI for detection of recurrent PCa in comparison to PET/CT. METHODS 48 patients with suspected recurrent PCa underwent PET/CT after injection of the 68Ga-HBED-CC-PSMA ligand followed by integrated PET/MRI. Image analysis was performed by nuclear medicine physicians and radiologists with respect to the detection of lymph nod...

The exploration of the human connectome, a term denoting the global structural connectivity of the brain, is accessible to MRI at millimeter and centimeter scales. In this paper, we propose a methodology to map the connectome by constructing normalized whole-brain structural connection matrices derived from diffusion spectrum MRI tractography. Using a template-based approach, we propose a robus...