نتایج جستجو برای: mir 137
تعداد نتایج: 58857 فیلتر نتایج به سال:
miR-137 and miR-491 Negatively Regulate Dopamine Transporter Expression and Function in Neural Cells
Lineage progression in osteoblasts and chondrocytes is stringently controlled by the cell-fate-determining transcription factor Runx2. In this study, we directly addressed whether microRNAs (miRNAs) can control the osteogenic activity of Runx2 and affect osteoblast maturation. A panel of 11 Runx2-targeting miRNAs (miR-23a, miR-30c, miR-34c, miR-133a, miR-135a, miR-137, miR-204, miR-205, miR-217...
Joachim Silber ([email protected]) Daniel A Lim ([email protected]) Claudia Petritsch ([email protected]) Anders I Persson ([email protected]) Alika K Maunakea ([email protected]) Mamie Yu ([email protected]) Scott R Vandenberg ([email protected]) David G Ginzinger ([email protected]) C David James ([email protected]) Joseph F Costello (Joseph.Costello@uc...
BACKGROUND MicroRNAs (miRNAs or miRs) are post-transcriptional regulators of eukaryotic cells and knowledge of differences in miR levels may provide new approaches to diagnosis and therapy. METHODS The present study measured the levels of nine miRs in head and neck squamous cell carcinomas (HNSCC) and determined whether clinical pathological features are associated with differences in miR lev...
Cervical cancer and a subset of anogenital and head-and-neck carcinomas are caused by high-risk types of the human papillomavirus (hrHPV). During hrHPV-induced malignant transformation keratinocytes become able to grow anchorage independently, a tumorigenic trait at least partly associated with inactivation of tumor suppressor genes. We used hrHPV-containing keratinocytes to investigate the rol...
Spermatogenesis is a multistep synchronized process. Diploid spermatogonia differentiate into haploid spermatozoa following mitosis, meiosis and spermiogenesis. Division and differentiation of male germ cells is achieved through the sequential expression of several genes. Numerous mRNAs in the differentiating germ cells undergo post-transcriptional and translational regulation. MiRNAs are power...
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