this paper focuses on the optimization of initiating dimensions of groove bearing in association with de- sired design of vehicle’s front structure which is made up of low carbon steels in the case of frontal collision. axial bearing analysis is done numerically using nonlinear finite element code ls-dyna. in this analysis, changes of two main parameters including measure of energy absorption o...

A great number and variety of homogeneous lanthanide catalysts are now used in industry and academia as low-cost, low-toxicity, Lewis acidic, and coordination catalysts. In the search for new asymmetric catalysts, chiral C3-symmetric complexes are emerging as interesting competitor systems to the ubiquitous C2-symmetric systems. [2] Trivalent lanthanide cations are obvious candidates for the de...

Objectives To evaluate the risk of all cause mortality associated with initiating compared with not initiating benzodiazepines in adults, and to address potential treatment barriers and confounding related to the use of a non-active comparator group.Design Retrospective cohort study.Setting Large de-identified US commercial healthcare database (Optum Clinformatics Datamart).Participants 1:1 hig...

Fibrosis, characterized by excessive extracellular matrix accumulation, is a common feature of many connective tissue diseases, notably scleroderma (systemic sclerosis). Experimental studies suggest that a complex network of intercellular interactions involving endothelial cells, epithelial cells, fibroblasts and immune cells, using an array of molecular mediators, drives the pathogenic events ...

Chloroform and other trihalomethanes are contaminants of drinking water that have been demonstrated to be carcinogenic in laboratory animals. Determination of the mechanism of carcinogenicity of chloroform is required so that the animal data can be extrapolated to estimate the human health hazard. The extent of the binding of chloroform to rat liver and kidney DNA was approximately 0.1% the lev...