Filaggrin is a component of the cornified cell envelope and the precursor of free amino acids acting as a natural moisturizing factor in the stratum corneum. Deimination is critical for the degradation of filaggrin into free amino acids. In this study, we tried to identify the enzyme(s) responsible for the cleavage of deiminated filaggrin in vitro. First, we investigated citrulline aminopeptida...

objective to determine and compare the spf (sun protection factor) and moisturizing effects of the liposomal and conventional lotion formulations containing octyl methoxycinnamte (omc) as a sunscreen by in vivo methods. materials and methods the multilamellar liposomes (mlvs) containing omc were prepared by fusion method and o/w emulsion was prepared as fda standard sunscreen method. the spfs o...

Bacterial cellulose (BC) produced by certain bacteria has the potential to be used in many different areas. Despite its advantageous properties compared plant cellulose, such as high purity, mechanical strength, nanofiber mesh structure, and high-water holding capacity, production through a biotechnological process prevents it from competing with counterparts terms of cost-effectiveness. Theref...

Xerosis is a common skin condition as well key aspect of number diseases associated to hereditary and acquired conditions. The objective this study was formulate evaluate the pluronic lecithin organogel containing natural moisturizing agents for topical application. Different formulations organogels were prepared by using Pluronic F127, Lecithin, Vitamin E, Aloe vera, water, sorbic acid, potass...