Analytic solutions are obtained for the equilibria of a simple two-locus, heterotic selection model with mixed selfing and random outcrossing. Two general phenomena are possible, depending upon the viabilities and the degree of selfing: (1) Negative disequilibrium potential, under which only gametic disequilibrium is possible; and (2) positive disequilibrium potential, which can result in perma...

In this paper we formulate a baseline disequilibrium AS-AD model and empirically estimate it with time series data for the US-economy. The version of the model used here exhibits a Phillips-curve, a dynamic IS curve and a Taylor interest rate rule. It is based on sticky wages and prices, perfect foresight of current inflation rates and adaptive expectations concerning the inflation climate in w...

Abstract Government policy has placed increasing emphasis on the need for robust labour market projections. The job vacancy rate is a key indicator of state economy underpinning most monetary decisions. However, its variation over time rarely studied in relation to employment variations, especially at sectoral level. present paper assesses whether changes number vacancies from quarter are leadi...

The evolution of macroeconomic theory and monetary policy has brought us to a point that calls for critical reflection. It is undoubtedly true that no newcomer to the field can even begin to understand the current state of macroeconomics and policy formulation without understanding just how, dating from the pre-Keynesian era, the profession has arrived at this state. High theory today takes the...

High rates of climate change are currently exceeding many plant species' capacity to keep up with climate, leading mismatches between climatic conditions and preferences the species present in a community. This disequilibrium community composition could diminish, however, when critical thresholds exceeded, due population declines or losses among more mismatched species. Here, we assessed effect...

Price stability has been the foremost task of monetary policy. The information relating to the response of prices to monetary policy shocks is essential for conducting monetary policy in general and for inflation targeting of central banks in particular. Most of the published empirical studies analyze the response of an aggregate price index like CPI or a consumption deflator and their r...

The frequently reported amino acid covariation of the highly polymorphic human immunodeficiency virus type 1 (HIV-1) exterior envelope glycoprotein V3 region has been assumed to reflect fitness epistasis between residues. However, nonrandom association of amino acids, or linkage disequilibrium, has many possible causes, including population subdivision. If the amino acids at a set of sequence s...