BACKGROUND A previously developed monoclonal/polyclonal ELISA (Mono/Poly) to detect plasma concentrations of osteopontin (OPN) was shown to provide prognostic information in breast, prostate, and other cancers. Here we describe the clinical validation of a new dual monoclonal (Dual Mono) assay. We compared both assays with 4 assays that recognize defined regions of OPN protein (dual polyclonal ...

Adiponectin is an important marker of anthropometric profiles of adipose tissue. However, association of adiponectin and adiposity in HIV mono- and co-infected and hepatitis (HCV) injection drug users (IDUs) has not been elucidated. Therefore, the relationship of total adiponectin levels with anthropometric indices of adiposity was examined in HIV mono-infected (anti-retroviral treatment, ART-n...

BACKGROUND Subjects submitted to intravenous (IV) blood transfusions for medical reasons or blood doping to increase athletic performance are potentially exposed to the plasticizer di-(2-ethylhexyl)phthalate (DEHP) found in IV bags. Exposure to DEHP has been evaluated by measuring DEHP metabolites in selected groups of subjects. STUDY DESIGN AND METHODS Urinary DEHP metabolites, mono-(2-ethyl...

Emerging evidence suggests that ubiquitination serves as a protein trafficking signal in addition to its well characterized role in promoting protein degradation. The yeast G protein alpha subunit Gpa1 represents a rare example of a protein that undergoes both mono- and poly-ubiquitination. Whereas mono-ubiquitinated Gpa1 is targeted to the vacuole, poly-ubiquitinated Gpa1 is directed instead t...

Unmanned aerial systems (UASs) have recently become an affordable means to map forests at the species level, but research into performance of different classification methodologies and sensors is necessary so users can make informed choices that maximize accuracy. This study investigated whether multi-temporal UAS data improved classified accuracy 14 examined optimal time-window for collection,...

LST has been fluctuating more quickly, resulting in the degradation of climate and human life on a local–global scale. The main aim this study is to examine SUHI formation hotspot identification over Prayagraj city India using seasonal Landsat imageries 1987–2018. interrelationship between six land indices (NDBI, EBBI, NDMI, NDVI, NDWI, SAVI) (using mono-window algorithm) was investigated by an...

The known ore deposits and mineralization trends are important key exploration criteria in mineral exploration within a specific region. Fry analysis has conventionally been considered as a suitable method to determine the mineralization trends related to linear structures. Based upon literature sources, to date, no investigation has been carried out that includes the Sensitivity Analysis of Fe...