Abstract The tightening emission regulations have led to the development of commercial DOCs with zoned or layered formulations allowing cover a wide range functionalities (i.e. CO, HC and NO oxidation as well NOx trap). Aging phenomena in such complex are not understood. To shed light on material deactivation, this study compares phosphorus poisoning thermal sintering two DOC monoliths related ...

The migration of monolithic applications to the cloud is a popular trend, with microservice architecture being commonly targeted architectural pattern. motivation behind this often rooted in challenges associated maintaining legacy and need adapt rapidly changing business requirements. To ensure that microservices sound decision for enhancing maintainability, designers must carefully consider u...

Affinity chromatography is an important and useful tool for studying biological interactions, such as the binding of an antibody with an antigen. Monolithic supports offer many advantages over traditional packed bed supports in affinity chromatography, including their ease of preparation, low back pressures and good mass transfer properties. Monoliths can be broken down into two basic categorie...

The potential of integration of functions in microfluidic chips is demonstrated by implementing on-chip preconcentration of proteins prior to on-chip protein sizing by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Two polymeric elements-a thin (approximately 50 microm) size exclusion membrane for preconcentration and a longer (approximately cm) porous monolith for protei...

This application note describes how the Agilent Bio-Monolith Protein A column was applied to the optimization of Chinese hamster ovary cell-culture conditions to produce a recombinant monoclonal antibody with desired structural characteristics, focusing on glycosylation. The workflow demonstrates the versatility and wide applicability of the column in biopharmaceutical and biosimilar development.

Mesoporous polyacrylonitrile (PAN) monolith has been fabricated by a template-free approach using the unique affinity of PAN towards a water/dimethyl sulfoxide (DMSO) mixture. A newly developed Thermally Induced Phase Separation Technique (TIPS) has been used to obtain the polymer monoliths and their microstructures have been controlled by optimizing the concentration and cooling temperature.

This paper presents a component-based framework for designing simulation models and discusses its implementation in a package called Simkit. In this framework, Components are defined to be monolith software entities that interact with other components in one of only three ways. Although seemingly restrictive, this approach supports more extensibility and customization of simulation models than ...

The mixing of graphene oxide and protonated poly(m-phenylenediamine) (PmPD) nanoparticles generates floccus that can be readily transformed into graphene@PmPD hybrid hydrogel through redox reaction. This macroscopic material can be directly applied as a monolith column adsorbent for water purification.