The cerebellum is densely interconnected with sensory-motor areas of the cerebral cortex, and in man, the great expansion of the association areas of cerebral cortex is also paralleled by an expansion of the lateral cerebellar hemispheres. It is therefore likely that these circuits contribute to non-motor cognitive functions, but this is still a controversial issue. One approach is to examine e...

The incidence of stroke is increasing yearly, and the remaining upper limb motor dysfunction after still problematic for rehabilitation treatment. Proper assessment tools help gain additional feedback on effectiveness. Although many methods exist assessing extremity function in a clinical setting, Fugl-Meyer Upper Extremity Motor Scale most valid reliable. It has been translated into several la...

BACKGROUND To evaluate the clinical features and outcome of patients with progressive neurological deficits due to disc herniation who were treated surgically within 24 h. METHODS We conducted a retrospective analysis of consecutive patients who were admitted between 2004 and 2013 via the Emergency Department. Records were screened for presenting symptoms, neurological status at admission, di...

the proportion of elderly in the general population is rising, resulting in greater numbers of drivers with neurodegenerative disorders such as alzheimer’s disease (ad) and parkinson’s disease (pd). alzheimer’s disease is a progressive neurodegenerative disorder typified by memory impairment with executive dysfunction, motor problems, and/or language difficulties. parkinson’s disease is a progr...

BACKGROUND Scalp acupuncture has shown a remarkable treatment efficacy on motor dysfunction in patients with stroke in China, especially the motor area of Jiao's scalp acupuncture, which is the most widely used treatment. However, previous studies have summarized that the clinical curative effect of acupuncture treatment for stroke remains uncertain. Meanwhile, no randomized controlled trials o...

Objective(s): Parkinson's disease (PD) is a progressive neurological disorder associated with motor disabilities and cognitive dysfunction as well. Evidence indicates that PD occurs less frequently in women than men, confirming a role for steroid hormones in protection of dopaminergic nigrostriatal neurons. It is reported that soy genistein, an estrogen agonist phytoestrogen, display neuroprote...

Establishing the neurological basis of behavioural dysfunction is key to provide a better understanding of Parkinson's disease (PD) and facilitate development of effective novel therapies. For this, the relationships between longitudinal structural brain changes associated with motor behaviour were determined in a rat model of PD and validated by post-mortem immunohistochemistry. Rats bearing a...

Efforts to explain the underlying pathophysiology of somatic dysfunction have emphasized the role of the somatic and autonomic motor systems. Evidence reviewed here indicates that sensory, dorsal root neurons may also act in a motor fashion to contribute to peripheral changes that may be involved in somatic dysfunction. The peripheral effects of antidromic activity in sensory nociceptive neuron...

Introduction: Alzheimer’s Disease (AD) is a chronic neurological disorder characterized by memory impairment, cognitive dysfunction, behavioral disturbances, and deficits in activities of daily living. AD has been found to be associated with a cholinergic deficit in the post-mortem brain characterized by a significant decrease in acetylcholine amount and loss of cholinergic neurons of the nu...