Background: Placental mesenchymal dysplasia (PMD) is a distinct syndrome of unknown aetiology that associated with significant fetal morbidity and mortality. Intrauterine growth restriction common, yet, paradoxically, many the fetuses/newborns have been diagnosed Beckwith-Wiedemann (BWS). Methods: We report two cases PMD high levels androgenetic (complete paternal uniparental isod...

Hair follicles play an important role in hair development. This study aimed to develop a microgel-spotting device fabricate multilayered gel bead culture model and mimic the early development of skin appendages regenerate vitro. The consists alginate layer containing cytokines as core layer, collagen mouse embryonic stem cells middle fetus-derived epidermal outer layer. A concentration gradient...

Water homeostasis during fetal development is of crucial physiologic importance. It depends upon maternal fetal fluid exchange at the placenta and fetal membranes, and some exchange between fetus and amniotic fluid can occur across the skin before full keratinization. Lungs only grow and develop normally with fluid secretion, and there is evidence that cerebral spinal fluid formation is importa...

Multiple processes are capable of activating the onset of parturition; however, the specific contributions of the mother and the fetus to this process are not fully understood. In this issue of the JCI, Gao and colleagues present evidence that steroid receptor coactivators 1 and 2 (SRC-1 and SRC-2) regulate surfactant protein-A (SP-A) and platelet-activating factor (PAF) expression, which incre...

introduction maternal and fetal characteristics can be effect on optimism which vary among different cultures and countries. so the aim of this study was to determine prenatal optimism and its relationship with fetal and maternal characteristics in primiparous women. materials and methods this research study was a descriptive cross - sectional. the statistical populations consisted of 240 pregn...

ABSTRACT In mammals, 24-h rhythms of physiology and behavior are organized by a body-wide network clock genes proteins. Despite the well-known function adult circadian system, roles maternal, fetal placental clocks during pregnancy poorly defined. mature mouse placenta, labyrinth zone (LZ) is origin key for selective nutrient waste exchange. Recently, gene expression has been detected in LZ oth...

Spring 2013 | Volume 7 Columbia Undergraduate Science Journal 10 Characterizing the Biomechanical and Biochemical Properties of Mouse Uterine Tissue Eli Mondragon*, Kyoko Yoshida, M.S. Kristin Myers, Ph.D Biomedical Engineering Department, Columbia University, New York, NY 10027 Mechanical Engineering Department, Columbia University, New York, NY 10027 Abstract For a successful pregnancy, the u...