BACKGROUND Gel polymers are considered as new dosimeters for determining radiotherapy dose distribution in three dimensions. OBJECTIVE The ability of a new formulation of MAGIC-f polymer gel was assessed by experimental measurement and Monte Carlo (MC) method for studying the effect of gold nanoparticles (GNPs) in prostate dose distributions under the internal Ir-192 and external 18MV radioth...

In this work gold nanoparticles (AuNP) were embedded in MAGIC-f gel and irradiated in a 250 kV x-ray clinical beam. The signal of non-irradiated gel samples containing AuNPs showed maximum difference of 0.5% related to gel without nanoparticles. Different AuNPs concentrations were studied: 0.10 mM, 0.05 mM and 0.02 mM, presenting dose enhancements of 106%, 90% and 77% respectively. Monte Carlo ...

Background: An effective polymer gel dosimeter can be fabricated by varying the composition of its chemical components. Materials and Methods: The MAGAT gel dosimeter formulations that used different compositions of Methacrylic acid (MAA) and gelatin were extensively investigated in the present study according to the R2–dose response and R2–dose sensitivity. The irradiation of M...

Since the introduction of volumetric chemical dosimetry with Fricke gel dosimeters in the 1980s, three-dimensional (3D) dosimetry has been a promising technique for the clinic, since it provides a unique methodology for 3D dose measurement of the complex conformal dose distributions achieved by modern techniques such as Intensity Modulated and Volumetric Arc Radiation Therapy. In the last decad...

Introduction: Magnetic resonance imaging dependent polymer gel dosimetry is a technique that offers unique advantages for implementing increasingly complex radiotherapy procedures, due to the high spatial resolution and volumetric dosimetry capabilities. The technique involves the estimation of radiation dose distribution based on the changes in MR relaxation parameters caused by radiation indu...

Raman spectroscopy are used to characterize the chemical changes in normoxic polyhydroxyethylacrylate gel dosimeter (PHEA) induced by radiation. Irradiations in the low dose region are performed and the polymerizations of PHEA gels are monitored by the observing the changes of Raman shift intensity of the carbon covalent bond of PHEA originated from both monomer and the cross-linker. The variat...