نتایج جستجو برای: multicellular spheroids

تعداد نتایج: 11490  

Journal: :Journal of The Mechanics and Physics of Solids 2023

The mechanism by which cells measure the dimension of organ in they are embedded, and slow down their growth when final size is reached, a long-standing problem developmental biology. role mechanics this feedback considered important. Morphoelasticity standard continuum framework for modeling growing elastic tissues. However, theory, absence additional variables, between mechanical stress leads...

Journal: :Revista Brasileira Multidisciplinar 2021

Photobiomodulatory effects of low-intensity laser radiation (LILR) in cells cultured standard, two-dimensional conditions are well established. Conversely, the characteristics this effect three-dimensional (3D) cultures, which currently recommended due to greater similarity with cellular behavior vivo, have not yet been widely investigated. The objective work was analyze biomodulator LILR, on w...

Journal: :Applied optics 2007
Kwan Jeong John J Turek David D Nolte

Digital holographic optical coherence imaging is a full-frame coherence-gated imaging approach that uses a CCD camera to record and reconstruct digital holograms from living tissue. Recording digital holograms at the optical Fourier plane has advantages for diffuse targets compared with Fresnel off-axis digital holography. A digital hologram captured at the Fourier plane requires only a 2D fast...

2009
Hee-Won Jung Je G. Chi

= Abstract = Tumor .tissue obtained from seven human malignant gliomas was minced and explanted into agarose-coated culture plates. After five to seven days, these microtumor fragments emerged as spheroids in four tumors and were maintained as multicellular organotypic spheroids for more than eight weeks. The morphological features and growth characteristics of different spheroids were studied ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1993
H Kobayashi S Man C H Graham S J Kapitain B A Teicher R S Kerbel

EMT-6 murine mammary tumor sublines highly resistant to cyclophosphamide, cis-diamminedichloro-platinum(II), or N,N',N"-triethylenethiophosphoramide were generated in vivo by sequential treatment of tumor-bearing mice with the respective drugs. Previous studies demonstrated the drug-resistant phenotypes of the sublines were not expressed in vitro when the cells were grown as monolayer cultures....

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