Introduction: Recurrent disease following colorectal cancer surgery will occur in about 30-50% of patients when considering both locoregional relapse and distant metastasis. For patients with rectal cancer, preoperative chemoradiotherapy followed by TME can provide durable 10-years overall survival (OS) of 58% and recurrence-free survival (RFS) of 62%. Background: Despite optimal treatment with...

BACKGROUND Anaplastic thyroid cancer is a rare and lethal disease. It accounts for 1-2% of thyroid malignancies, but specific mortality is higher than 90%. It is an aggressive locoregional disease with a high metastatic capacity. There is no agreement with regards to the best treatment. We analysed the results of treatment in a mestizo population treated in the National Cancer Institute (Mexico...

Odontogenic ghost cell carcinoma (OGCC) is a rare and aggressive tumor wherein optimal treatment remains uncertain. We report the first pediatric metastatic OGCC case treated with multimodal therapy: surgery, adjuvant chemoradiation, and adjuvant immunotherapy. Adjuvant therapy was utilized due to locally advanced disease with pathologic features indicative of high recurrence risk. This multimo...

Background The treatment of malignant pleural mesothelioma (MPM) is challenging, and multimodal treatment including surgery is recommended; however, the role of surgery is debated. The treatment outcomes of MPM in Korea have not been reported. We analyzed the outcomes of MPM in the context of multimodal treatment, including surgery. Methods The records of 29 patients with pathologically prove...

BACKGROUND AND PURPOSE Stroke remains a common medical problem with importance attributable to the demographic changes in industrialized societies. SUMMARY OF REVIEW After years of setbacks, acute stroke therapy has finally emerged, including thrombolysis with tissue plasminogen activator (t-PA). However, t-PA treatment is limited by a narrow time window and side effects, so that only 3% of a...

The treatment of eating disorders is based on a multimodal model, recognizing that these disorders do not have a single cause or a predictable course. The treatment strategy is determined by the severity of illness and the specific eating disorder diagnosis. For the treatment of anorexia nervosa, the key elements are medical management, behavioral therapy, cognitive therapy and family therapy, ...

Rhabdomyosarcoma is the most frequent mesenchymal tumor in children, composed of cells with histopathological characteristics striated muscle at different stages embryogenesis. The orbital location accounts for about 10% cases. Its prognosis has improved thanks to progress chemotherapy and new radiotherapy techniques.The aim our study report clinical therapeutic rhabdomyosarcomas orbit present ...

Head and neck cancers are relatively less common tumors, but with complex anatomic and physiologic relationships to the structures from which they arise. Multimodal management is required for advanced stage disease, while single modality treatment is usually sufficient for early lesions. Treatment paradigms have shifted toward more functional preservation of speech and swallowing, when possible...