iChirp-evoked auditory brainstem responses (ABRs) yield a larger wave V amplitude at low intensity levels than traditional broadband click stimuli, providing a reliable estimation of hearing sensitivity. However, advantages of iChirp stimulation at high intensity levels are unknown. We tested to see if high-intensity (i.e., 85 dBnHL) iChirp stimulation results in larger and more reliable ABR wa...

Background: Cell mediated immunity, especially cytotoxic T cell responses against HIV-1 infection, plays a critical role in controlling viral replication and disease progres-sion. DNA vaccine is a novel technology which is known to stimulate strong cellular immune responses. Many DNA vaccines have been tested for HIV infection but there is still no effective vaccine against this infection. Cons...

We introduced a generalised Wishart process (GWP) for modelling input dependent covariance matrices Σ(x), allowing one to model input varying correlations and uncertainties between multiple response variables. The GWP can naturally scale to thousands of response variables, as opposed to competing multivariate volatility models which are typically intractable for greater than 5 response variable...

Surveys often contain qualitative variables for which respondents may select any number of the outcome categories. For instance, for the question "What type of contraception have you used?" with possible responses (oral, condom, lubricated condom, spermicide, and diaphragm), respondents would be instructed to select as many of the outcomes that apply. This situation is known as multiple respons...

Bladder disturbances and sexual impotence are common and distressing disorders occurring in multiple sclerosis. Miller, Simpson, and Yeates (1965) found bladder complaints occurring at some time of the disease in 78% of 297 patients, and in 52% of them it had persisted for over six months, while sexual impotence due to physical disease occurred in 44% of their patients. Although these disturban...