BACKGROUND Although multivitamins are widely used, there are limited prospective studies investigating their association with both long- and short-term risk of cardiovascular disease (CVD). OBJECTIVE The objective was to investigate how multivitamin use is associated with the long- and short-term risk of CVD. DESIGN A prospective cohort study was conducted of 37,193 women from the Women's H...

Metformin, an insulin-sensitizing drug, is a first line treatment for type 2 diabetes. Long-term use of metformin has been associated with subsequent reductions in vitamin B12 concentrations. The objective of our study was to determine whether metformin use is associated with lower serum vitamin B12 concentrations in older adults, and whether concurrent use of multivitamins modifies this associ...

BACKGROUND The use of folic acid-fortified multivitamin supplements has long been associated with decreasing the risk of neural tube defects. Several studies have also proposed the effectiveness of these supplements in preventing other birth defects; however, such effects have never been systematically examined. OBJECTIVE We conducted a systematic review and meta-analysis to evaluate the prot...

BACKGROUND Women planning to conceive are often advised to take multivitamins. Whether this affects the survival of the fetus is not known. METHODS We used data from 35 914 women in the Danish National Birth Cohort who at recruitment had reported the number of weeks of supplement use during a 12-week periconceptional period. A telephone interview provided information about maternal characteri...

BACKGROUND Despite the increasing use of Roux-en-Y gastric bypass (RYGBP) in the treatment of morbid obesity, data about postoperative nutritional deficiencies and their treatment remain scarce. OBJECTIVE The aim of this study was to evaluate the efficacy of a standard multivitamin preparation in the prevention and treatment of nutritional deficiencies in obese patients after RYGBP. DESIGN ...

OBJECTIVE Understanding the relationship between multivitamin use and diabetes risk is important given the wide use of multivitamin supplements among U.S. adults. RESEARCH DESIGN AND METHODS We prospectively examined supplemental use of multivitamins and individual vitamins and minerals assessed in 1995-1996 in relation to self-reported diabetes diagnosed after 2000 among 232,007 participants...

Maternal nutrition is one of the most important factors affecting birth weight of infants. Vitamin is very important in this regard. Pregnant women’s need to multivitamin as well as their weight gain can lead to weight gain and birth weight in infants. Although body weight gain is desirable in most individuals with lower BMI, this matter could be problematic in those with high BMI. In this stud...

Background Patients with morbid obesity have a high risk of deficits in micronutrients, after bariatric surgery. The reasons why systematic use multivitamin and trace element supplements cannot prevent all are complex should deserve more attention. Little is known about the influence micronutrient at Aim This present study aimed to explore deficit vitamin B12 vs other micronutrients during foll...

The ability of cyclic square wave voltammetry to identify distinct fingerprints of multiple vitamins, in a single voltammetric run, is demonstrated. This method represents an efficient alternative to more common techniques for fast screening of complex vitamin mixtures or commercial tablets due to its low cost, high speed and sensitivity.

In this cohort study, the authors evaluated how supplemental use of multivitamins, vitamin C, and vitamin E over a 10-year period was related to 5-year total mortality, cancer mortality, and cardiovascular disease (CVD) mortality. Participants (n = 77,719) were Washington State residents aged 50-76 years who completed a mailed self-administered questionnaire in 2000-2002. Adjusted hazard ratios...