BACKGROUND Sarcopenia is strongly associated with an inadequate intake of dietary protein. Dietary protein supplementation boosts muscle-protein synthesis and increases muscle mass in the elderly. This study tested whether adding a protein-rich food, ricotta cheese, to the habitual diet increased total appendicular skeletal muscle mass and strength in elderly people. METHODS Participants (n =...

PURPOSE This study aimed to evaluate the hypothesis that exercise attenuates the reductions in lean mass, muscle strength, bone mineral density, and V˙O2max that accompany modest weight loss induced by calorie restriction (CR). METHODS Overweight, sedentary women and men (n = 52, 45-65 yr) were randomized to 6%-8% weight loss by using CR, endurance exercise training (EX), or both (CREX). The ...

background: the present study was conducted to investigate the possible effects of l-carnitine and glutamine and their synergistic effects on male soccer athletes. methods: 28 male soccer players (21.1±0.7 y) were enrolled in a randomized pre and post intervention, double-blind design. before the intervention, their performances were assessed by bruce protocol, and their body composition was me...

BACKGROUND Albuterol is a beta-2 agonist that has been demonstrated to increase muscle strength in studies in animals and humans. Based on a pilot study of extended-release albuterol Repetabs in children with dystrophinopathies, the authors conducted a randomized, double-blind, placebo-controlled study with a crossover design. METHODS Fourteen boys with Duchenne or Becker muscular dystrophy, ...

OBJECTIVES To examine the association between strength, function, lean mass, muscle density, and risk of hospitalization. DESIGN Prospective cohort study. SETTING Two U.S. clinical centers. PARTICIPANTS Adults aged 70 to 80 (N=3,011) from the Health, Aging and Body Composition Study. MEASUREMENTS Measurements were of grip strength, knee extension strength, lean mass, walking speed, and ...

Background: One of the important issues in aging is sarcopenia characterized by muscle mass and function reduction. The present study investigated the effect of high intensity interval resistance training (HIIRT) on muscular parameters in sarcopenic elderly women. Methods: A total of 30 sarcopenic women aged 60 to 70 years (appendicular skeletal muscle mass index<6.76 kg/m2, hand grip<20 kg) w...

BACKGROUND N-terminal peptide of procollagen type III (P3NP) and C-terminal agrin fragment (CAF) are circulating biomarkers that are related to lean body mass in older adults. P3NP is a circulating marker reflective of muscular structural remodeling while CAF is a circulating marker of neuromuscular remodeling. As resistance exercise is an established intervention that can effectively improve m...

BACKGROUND In a cross-sectional study in 403 healthy, independently living elderly men (mean age 78 years), we determined which are the main physiological determinants of functional ability in the elderly, and which components of the somatotropic system contribute to the maintenance of functional ability. METHODS Functional ability was assessed by the number of problems in activities of daily...

Background: It is well documented that cigarette smoking has negative impacts on body health, as well as social health, economy, culture, etc. Nowadays, there is a large body of evidence that smoking is the cause of numerous life-threatening diseases like cardiovascular and pulmonary diseases along with different kinds of cancer. The aim of this study was to compare the physical fitness of smok...

The purpose of this study was to investigate the changes in the body composition, body size, muscle strength, and VO2max after 24 weeks of resistance or endurance training and detraining in young men. Thirty healthy college-aged men (20.4 ± 1.36 years) participated in the study. Subjects were assigned to resistance training group (RTG, n = 10), endurance training group (ETG, n = 10), and contro...