BACKGROUND Thymectomy is the primary approach for the treatment of myasthenia gravis (MG). This retrospective study aimed to identify the clinical and demographical features that may impact the duration of mechanical ventilation (DMV), the long-term survival, and the quality of life (QOL) in patients with post-thymectomy myasthenic crisis (PTMC). METHODS We reviewed the patients who suffered ...

The patient is a 62-year-old man who was diagnosed with myasthenia gravis and invasive thymoma at the age of 45 years, and had received treatment by extended thymectomy and radiotherapy. At the age of 61, he had suffered from a myasthenic crisis, and been administered immunoadsorption therapy under managed ventilatory care. Treatment had then been continued with steroids; however, due to subseq...

OBJECTIVES Autoimmune thyroid diseases (ATDs) frequently accompany myasthenia gravis (MG) and may influence its course. We aimed to determine the association and impact of ATD with early- (<50 years), late-onset MG, or thymoma-MG. MATERIALS AND METHODS Prevalence of ATD was measured in a cross-sectional study of 343 consecutive patients with MG (236 F, 107 M) aged 4-89 years; 83.8% were serop...

Though the pathogenesis of myasthenia gravis (MG) is not fully understood, the role of inflammation has been well appreciated in the development of MG. We aimed to investigate the role of neutrophil-to-lymphocyte ratio (NLR) in MG patients and the relationship between the NLR and the activity of the disease. A total number of 172 MG patients and 207 healthy controls (HC) were enrolled in this s...

myasthenia gravis (mg) is a disorder of the neuromuscular junction. in children, the disease may be congenital or due to an autoimmune process. clinical manifestations may be purely ocular or may include generalized weakness, fatigability, dysphagia, and disorders of speech. in this article, 27 children (14 female, 13 male) were prospectively studied from birth to age fifteen. disease presentat...

a retrospective comparative study was performed on 54 patients treated medically or surgically (thymectomy) for myasthenia gravis (mg) from 1979- 1989 in three shiraz university hospitals. each surgical patient was compared with a medical patient on the basis of age, sex, severity and duration of disease. complete remission was noted in 3 out of 27 thymectomized patients but in none of the medi...

BACKGROUND The Quantitative Myasthenia Gravis Score and the Myasthenia Gravis Composite are two commonly used outcome measures in Myasthenia Gravis. So far, their measurement properties have not been compared, so we aimed to study their psychometric properties using the Rasch model. METHODS 251 patients with stable myasthenia gravis were assessed with both scales, and 211 patients returned fo...

BACKGROUND Clinical predictors for myasthenia gravis relapse and ocular myasthenia gravis secondary generalization during the first two years after disease onset remain incompletely identified. This study attempts to investigate the clinical predictors for the prognosis of Myasthenia Gravis. METHODS Eighty three patients with myasthenia gravis were concluded in this study. Baseline characteri...

OBJECTIVES The aims of the current study were 1) to evaluate the reliability and validity of the Brazilian version of the 15-item Myasthenia Gravis Quality of Life Scale and 2) to investigate the quality of life of Brazilian patients with myasthenia gravis and its determinants. METHODS This cross-sectional study included 69 patients with myasthenia gravis who underwent neurological evaluation...