Photodynamic therapy involves the topical application of a photosensitizer to a lesion, which is then subsequently exposed to a light source. It is mainly used in the nonsurgical treatment of nonmelanoma skin cancer, in which it achieves good response and an excellent cosmetic result. In the last 10 years, photodynamic therapy has also been used with some success in the treatment of plaque-stag...

conclusions fmf should be considered in patients who present with alopecia, acne like lesions, cysts and comedones in older ages with a spectrum of histologic changes. we emphasize for any time it should be under-recognized. introduction folliculotropic mycosis fungoides (fmf) is a variant of mycosis fungoides characterized by the presence of folliculotropic atypical tcells infiltrates, often w...

The development of both a T- and B-cell lymphoproliferative disorder in one patient is an unlikely coincidence due to the low prevalence of each malignancy. We report a 65-year-old man with a previously documented history of B hairy cell leukemia, who presented with a new-onset acneiform eruption of his scalp, face, trunk, back, and extremities. Routine pathology of the skin lesions with immuno...

Figure 3. Scalp with prominent epidermal and follicular involvement by atypical lymphocytes (50x). Abstract We present an atypical case of Sézary syndrome in a 46-year-old African American female who presented with tenderness, pruritus, hyperpigmented lesions and lymphadenopathy. Her condition was characterized by the retention of T-cell CD7 expression, significant atypical lymphocytic epidermo...

Oral involvement in mycosis fungoides is unusual and portends a poor prognosis. The clinical findings of three new cases are described along with a differential diagnosis and review of the literature. For brevity, only one patient is discussed in detail below whereas the other two cases are solely described in table form. The patient had a four-year history of mycosis fungoides before developin...

We describe two unique cases of fulminant mycosis fungoides with remarkably similar and aggressive clinical courses resulting in death. Both cases demonstrated ulcerated palmar and periorbital plaques and marked tissue eosinophilia, which was confirmed by T-cell receptor γ chain gene rearrangement studies to display identical monoclonality at temporally and anatomically distinct sites. Dense eo...

conclusion there was no association between hhv-8 and mf or lpp in iranian population. this is in accordance with most of the reports from different countries. results the investigated samples consisted of 13 patient with mf, 10 patients with lpp, and 23 patients with chronic dermatitis; the diagnosis of these skin conditions were confirmed histopathologically. the rt-pcr could not detect hhv-8...

in this case we report the detection of lymph node metastases in a 52 years old patient with mycosis fungoides utilising 18f- fdg-pet/ct which led to a change in the management of the patient.

Mycosis fungoides is a candidate for skin-directed therapies in its initial stages. In recent years, therapeutic options outside of the normal treatment recommendations such as topical imiquimod, topical tazarotene, topical methotrexate, excimer light sources, and photodynamic therapy have been published with variable results. These alternatives have been useful in cases of localized mycosis fu...